Rabbit ACADVL Polyclonal Antibody | anti-ACADVL antibody

ACADVL

Cat. Num. AAA8536541

• Gene Names: ACADVL; ACAD6; LCACD; VLCAD
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: Affinity purification
• Synonyms: ACADVL; Polyclonal Antibody; ACAD6; LCACD; VLCAD; anti-ACADVL antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity purification
• Sequence Length: 655

• Applicable Applications for anti-ACADVL antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500-1:2000; IHC: 1:50-1:200
• Immunogen: Recombinant protein of human ACADVL
• Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Preparation and Storage: Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.

Related Product Information for anti-ACADVL antibody

The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms.

NCBI and Uniprot Product Information

• NCBI GI #: 4557235
• NCBI GeneID: 37
• NCBI Accession #: NP_000009.1
• NCBI GenBank Nucleotide #: NM_000018.3
• UniProt Accession #: P49748; O76056; Q8WUL0; B4DEB6; F5H2A9
• Molecular Weight: 70kDa
• NCBI Official Full Name: very long-chain specific acyl-CoA dehydrogenase, mitochondrial isoform 1
• NCBI Official Synonym Full Names: acyl-CoA dehydrogenase very long chain
• NCBI Official Symbol: ACADVL
• NCBI Official Synonym Symbols: ACAD6; LCACD; VLCAD
• NCBI Protein Information: very long-chain specific acyl-CoA dehydrogenase, mitochondrial
• UniProt Protein Name: Very long-chain specific acyl-CoA dehydrogenase, mitochondrial
• Protein Family: Very long-chain specific acyl-CoA dehydrogenase
• UniProt Gene Name: ACADVL
• UniProt Synonym Gene Names: VLCAD; VLCAD

NCBI Description

The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Uniprot Description

Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons.