Rabbit anti-Human, Mouse ABCD2 Polyclonal Antibody | anti-ABCD2 antibody

ABCD2, ID (ABCD2, ALD1, ALDL1, ALDR, ALDRP, ATP-binding cassette sub-family D member 2, Adrenoleukodystrophy-like 1, Adrenoleukodystrophy-related protein) (APC)

Cat. Num. AAA6270486

• Gene Names: ABCD2; ALDR; ABC39; ALDL1; ALDRP; hALDR
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: ABCD2; Polyclonal Antibody; ID (ABCD2; ALD1; ALDL1; ALDR; ALDRP; ATP-binding cassette sub-family D member 2; Adrenoleukodystrophy-like 1; Adrenoleukodystrophy-related protein) (APC); Adrenoleukodystrophy-related protein; anti-ABCD2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-ABCD2 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: ABCD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276~306 amino acids from the Central region of human ABCD2.
• Conjugate: APC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western blot analysis of ABCD2 Antibody (Center) in mouse brain tissue lysates (35ug/lane). ABCD2 (arrow) was detected using the purified Pab.)

Related Product Information for anti-ABCD2 antibody

ABCD2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters.

Product Categories/Family for anti-ABCD2 antibody

Antibodies; Multi Drug Resistance (MDR)

References

Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009). Maier, E.M., et al. Biochem. Biophys. Res. Commun. 377(1):176-180(2008). Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008).

NCBI and Uniprot Product Information

• NCBI GI #: 9945308
• NCBI GeneID: 225
• NCBI Accession #: NP_005155
• NCBI GenBank Nucleotide #: NM_005164
• UniProt Accession #: Q9UBJ2; Q13210; Q2M3H9; B2RAM3
• Molecular Weight: 83,233 Da
• NCBI Official Full Name: ATP-binding cassette sub-family D member 2
• NCBI Official Synonym Full Names: ATP-binding cassette, sub-family D (ALD), member 2
• NCBI Official Symbol: ABCD2
• NCBI Official Synonym Symbols: ALDR; ABC39; ALDL1; ALDRP; hALDR
• NCBI Protein Information: ATP-binding cassette sub-family D member 2; adrenoleukodystrophy-like 1; adrenoleukodystrophy-related protein
• UniProt Protein Name: ATP-binding cassette sub-family D member 2
• Protein Family: ABC transporter D family
• UniProt Gene Name: ABCD2
• UniProt Synonym Gene Names: ALD1; ALDL1; ALDR; ALDRP; hALDR
• UniProt Entry Name: ABCD2_HUMAN