Western Blot (WB)
(ABCB10 Antibody (S16) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the ABCB10 antibody detected the ABCB10 protein (arrow).)
Rabbit anti-Human ABCB10 Polyclonal Antibody | anti-ABCB10 antibody
ABCB10, NT (ABCB10, ATP-binding cassette sub-family B member 10, mitochondrial, ATP-binding cassette transporter 10, Mitochondrial ATP-binding cassette 2) (PE)
Gene Names
ABCB10; M-ABC2; MTABC2; EST20237
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
ABCB10; Polyclonal Antibody; NT (ABCB10; ATP-binding cassette sub-family B member 10; mitochondrial; ATP-binding cassette transporter 10; Mitochondrial ATP-binding cassette 2) (PE); mitochondrial ATP-binding cassette 2; anti-ABCB10 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Applicable Applications for anti-ABCB10 antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes
IHC: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
ABCB10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7~37 amino acids from the N-terminal region of human ABCB10.
Conjugate
PE
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(ABCB10 Antibody (S16) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the ABCB10 antibody detected the ABCB10 protein (arrow).)
Western Blot (WB)
(ABCB10 Antibody (S16) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the ABCB10 antibody detected the ABCB10 protein (arrow).)
Immunohistochemistry (IHC)
(ABCB10 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ABCB10 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(ABCB10 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ABCB10 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-ABCB10 antibody
The membrane-associated protein ABCB10 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The function of this mitochondrial protein is unknown.
Product Categories/Family for anti-ABCB10 antibody
References
Zhang, F., et al., J. Biol. Chem. 275(30):23287-23294 (2000). Allikmets, R., et al., Mamm. Genome 6(2):114-117 (1995). Zhang, F., et al., FEBS Lett. 478 (1-2), 89-94 (2000).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
79,148 Da
NCBI Official Full Name
ATP-binding cassette sub-family B member 10, mitochondrial
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family B (MDR/TAP), member 10
NCBI Official Symbol
ABCB10
NCBI Official Synonym Symbols
M-ABC2; MTABC2; EST20237
NCBI Protein Information
ATP-binding cassette sub-family B member 10, mitochondrial; ABC transporter 10 protein; ATP-binding cassette transporter 10; mitochondrial ATP-binding cassette 2
UniProt Protein Name
ATP-binding cassette sub-family B member 10, mitochondrial
Protein Family
UniProt Gene Name
ABCB10
UniProt Synonym Gene Names
ABC transporter 10 protein; M-ABC2
UniProt Entry Name
ABCBA_HUMAN
Uniprot Description
ABCB10: May mediate critical mitochondrial transport functions related to heme biosynthesis. Belongs to the ABC transporter superfamily. ABCB family. Mitochondrial peptide exporter (TC 3.A.1.212) subfamily.
Protein type: Hydrolase; Membrane protein, multi-pass; Transporter; Mitochondrial; Transporter, ABC family; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1q42.13
Cellular Component: mitochondrial inner membrane
Molecular Function: protein homodimerization activity; ATPase activity, coupled to transmembrane movement of substances; transporter activity; ATP binding
Biological Process: transport; metabolic process; transmembrane transport
Similar Products
Product Notes
The ABCB10 abcb10 (Catalog #AAA6270385) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ABCB10, NT (ABCB10, ATP-binding cassette sub-family B member 10, mitochondrial, ATP-binding cassette transporter 10, Mitochondrial ATP-binding cassette 2) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ABCB10 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:10-50 FLISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the ABCB10 abcb10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ABCB10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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