Rabbit anti-Human ABCA12 Polyclonal Antibody | anti-ABCA12 antibody

ABCA12 Antibody

Cat. Num. AAA9609561

• Gene Names: ABCA12; LI2; ICR2B; ARCI4A; ARCI4B
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
• Synonyms: ABCA12; Polyclonal Antibody; ABCA12 Antibody; ABC transporter A family member 12; ABC transporter ABCA.12; ABC12; ABCAC_HUMAN; AtABCA12; ATH16; ATP binding cassette 12; ATP binding cassette sub family A (ABC1) member 12; ATP binding cassette sub family A member 12; ATP binding cassette transporter 12; ATP-binding cassette 12; ATP-binding cassette sub-family A member 12; ATP-binding cassette transporter 12; Ichthyosis congenita II lamellar ichthyosis B; ICR2B; LI2; Putative ABC2 homolog 16; anti-ABCA12 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: ABCA12 antibody detects endogenous levels of total ABCA12
• Purity/Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
• Form/Format: Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: ~1mg/ml (varies by lot)
• Sequence Length: 2277

• Applicable Applications for anti-ABCA12 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:1000-3000; ELISA (peptide): 1:20000-1:40000; The optimal dilution should be determined by the end user.; IMPORTANT: For western blots, incubate membrane with diluted antibody in 5% w/v milk , 1X TBS, 0.1% Tween®20 at 4°C with gentle shaking, overnight.
• Immunogen: A synthesized peptide derived from human ABCA12, corresponding to a region within C-terminal amino acids.
• Preparation and Storage: Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of extracts from DU145 cells, using ABCA12 Ab. The lane on the left was treated with blocking peptide)

Related Product Information for anti-ABCA12 antibody

Function: Probable transporter involved in lipid homeostasis.
Similarity: Multifunctional polypeptide with two homologous halves, each containing a hydrophobic membrane-anchoring domain and an ATP binding cassette (ABC) domain. Belongs to the ABC transporter superfamily. ABCA family.

NCBI and Uniprot Product Information

• NCBI GI #: 27881501
• NCBI GeneID: 26154
• NCBI Accession #: NP_056472.2
• NCBI GenBank Nucleotide #: NM_015657.3
• UniProt Accession #: Q86UK0; Q53QE2; Q53S55; Q8IZW6; Q96JT3; Q9Y4M5
• Molecular Weight: Observed: 293 kDa; Predicted: 294 kDa
• NCBI Official Full Name: ATP-binding cassette sub-family A member 12 isoform b
• NCBI Official Synonym Full Names: ATP binding cassette subfamily A member 12
• NCBI Official Symbol: ABCA12
• NCBI Official Synonym Symbols: LI2; ICR2B; ARCI4A; ARCI4B
• NCBI Protein Information: ATP-binding cassette sub-family A member 12
• UniProt Protein Name: ATP-binding cassette sub-family A member 12
• Protein Family: ABC transporter A family
• UniProt Gene Name: ABCA12
• UniProt Synonym Gene Names: ABC12; ATP-binding cassette 12

NCBI Description

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily, which is the only major ABC subfamily found exclusively in multicellular eukaryotes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Uniprot Description

Probable transporter involved in lipid homeostasis.