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Testing Data

Rabbit ABCA1 Polyclonal Antibody | anti-ABCA1 antibody

ABCA1 Antibody

Gene Names
ABCA1; TGD; ABC1; CERP; ABC-1; HDLDT1
Reactivity
Human
Predicted: Mouse, Rat
Applications
ELISA, Western Blot
Synonyms
ABCA1; Polyclonal Antibody; ABCA1 Antibody; anti-ABCA1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Rat
Clonality
Polyclonal
Form/Format
Purified by protein A column containing 0.02% NaN3
Sequence Length
2261
Applicable Applications for anti-ABCA1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: 1:10,000-1:80,000
WB: 1:1,000-1:2,000
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.

Testing Data

Testing Data
Related Product Information for anti-ABCA1 antibody
Rabbit polyclonal ABCA1 (1) antibody was raised against a recombinate human ABCA1 protein 2085-2245aa (NM_005502).
References
(1) Iwamoto, N., Lu, R., Tanaka, N., et al. Calmodulin interacts with ATP binding cassette transporter A1 to protect from calpain-mediated degradation and upregulates high-density lipoprotein generation. Arterioscler. Thromb. Vasc. Biol. 30 (7), 1446-1452 (2010).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
19
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
254,302 Da
NCBI Official Full Name
ATP-binding cassette sub-family A member 1
NCBI Official Synonym Full Names
ATP binding cassette subfamily A member 1
NCBI Official Symbol
ABCA1
NCBI Official Synonym Symbols
TGD; ABC1; CERP; ABC-1; HDLDT1
NCBI Protein Information
ATP-binding cassette sub-family A member 1
UniProt Protein Name
ATP-binding cassette sub-family A member 1
Protein Family
UniProt Gene Name
ABCA1
UniProt Synonym Gene Names
ABC1; CERP; ABC-1; ATP-binding cassette 1

NCBI Description

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency. [provided by RefSeq, Jul 2008]

Uniprot Description

cAMP-dependent and sulfonylurea-sensitive anion transporter. Key gatekeeper influencing intracellular cholesterol transport.

Research Articles on ABCA1

Similar Products

Product Notes

The ABCA1 abca1 (Catalog #AAA853513) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ABCA1 Antibody reacts with Human Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ABCA1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:10,000-1:80,000 WB: 1:1,000-1:2,000. Researchers should empirically determine the suitability of the ABCA1 abca1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ABCA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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