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Rabbit anti-Human AATK Polyclonal Antibody | anti-AATK antibody

AATK (N-Term) Rabbit pAb

Reactivity
Human
Applications
Western Blot
Purity
Affinity Purified
Synonyms
AATK; Polyclonal Antibody; AATK (N-Term) Rabbit pAb; Serine/threonine-protein kinase LMTK1; Apoptosis-associated tyrosine kinase; AATYK; Brain apoptosis-associated tyrosine kinase; CDK5-binding protein; Lemur tyrosine kinase 1; p35-binding protein; p35BP; KIAA0641; LMR1; LMTK1; anti-AATK antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Ig
Purity/Purification
Affinity Purified
Form/Format
Supplied in PBS with 0.09% (W/V) Sodium Azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Length
589
Applicable Applications for anti-AATK antibody
Western Blot (WB)
Application Notes
WB: 1:2000
Immunogen
This AATK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-74 amino acids from the N-terminal region of human AATK.
Cellular Localization
Cytoplasm, Membrane

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
NCBI Official Full Name
AATK protein, partial
UniProt Protein Name
Serine/threonine-protein kinase LMTK1
UniProt Gene Name
AATK
UniProt Synonym Gene Names
AATYK; KIAA0641; LMR1; LMTK1; AATYK; p35BP
UniProt Entry Name
LMTK1_HUMAN

Uniprot Description

Lmr1: a protein kinase kinase of the Lmr family. Predominantly expressed in the nervous system and is involved in neurite extension and apoptosis of cerebellar granule cells. Contains a tyrosine kinase domain at the N-terminal end and a proline-rich domain at the C-terminal end. May be necessary for the induction of growth arrest and/or apoptosis of myeloid cells induced by cytokine withdrawal, such as IL3, and during G-CSF-induced terminal differentiation of myeloblasts to granulocytes. Four alternatively spliced isoforms have been reported.

Protein type: Protein kinase, TK; Protein kinase, tyrosine (receptor); EC 2.7.11.1; Membrane protein, integral; Kinase, protein; TK group; Lmr family

Chromosomal Location of Human Ortholog: 17q25.3

Cellular Component: recycling endosome; perinuclear region of cytoplasm; endoplasmic reticulum; integral to membrane

Molecular Function: protein serine/threonine kinase activity; protein binding; protein-tyrosine kinase activity; ATP binding

Biological Process: neuron apoptosis; negative regulation of axon extension; brain development; Rab protein signal transduction

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Product Notes

The AATK aatk (Catalog #AAA8556830) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AATK (N-Term) Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AATK can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:2000. Researchers should empirically determine the suitability of the AATK aatk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AATK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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