Western Blot (WB)
(All lanes : Anti-AATK Antibody (N-Term) at 1:2000 dilutionLane 1: Hela whole cell lysatesLane 2: NIH/3T3 whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 145 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Rabbit anti-Human, mouse AATK Polyclonal Antibody | anti-AATK antibody
AATK Antibody (N-Term)
Western Blot (WB)
(All lanes : Anti-AATK Antibody (N-Term) at 1:2000 dilutionLane 1: Hela whole cell lysatesLane 2: NIH/3T3 whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 145 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Western Blot (WB)
(All lanes : Anti-AATK Antibody (N-Term) at 1:2000 dilutionLane 1: Hela whole cell lysatesLane 2: NIH/3T3 whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 145 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Ishikawa K.,et al.DNA Res. 5:169-176(1998).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
Honma N.,et al.Biochem. Biophys. Res. Commun. 310:398-404(2003).
Raghunath M.,et al.Brain Res. Mol. Brain Res. 77:151-162(2000).
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Uniprot Description
Lmr1: a protein kinase kinase of the Lmr family. Predominantly expressed in the nervous system and is involved in neurite extension and apoptosis of cerebellar granule cells. Contains a tyrosine kinase domain at the N-terminal end and a proline-rich domain at the C-terminal end. May be necessary for the induction of growth arrest and/or apoptosis of myeloid cells induced by cytokine withdrawal, such as IL3, and during G-CSF-induced terminal differentiation of myeloblasts to granulocytes. Four alternatively spliced isoforms have been reported.
Protein type: Kinase, protein; Membrane protein, integral; EC 2.7.11.1; Protein kinase, tyrosine (receptor); Protein kinase, TK; TK group; Lmr family
Chromosomal Location of Human Ortholog: 17q25.3
Cellular Component: recycling endosome; perinuclear region of cytoplasm; endoplasmic reticulum; integral to membrane
Molecular Function: protein serine/threonine kinase activity; protein binding; protein-tyrosine kinase activity; ATP binding
Biological Process: neuron apoptosis; brain development; negative regulation of axon extension; Rab protein signal transduction
Research Articles on AATK
Similar Products
Product Notes
The AATK aatk (Catalog #AAA9206001) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AATK Antibody (N-Term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's AATK can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:2000. Researchers should empirically determine the suitability of the AATK aatk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AATK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
