Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Human 2',5'-Oligoadenylate Synthetase Polyclonal Antibody | anti-OASL antibody
Polyclonal Antibody to 2',5'-Oligoadenylate Synthetase Like Protein (OASL)
Gene Names
OASL; OASL1; OASLd; TRIP14; TRIP-14; p59OASL; p59 OASL; p59-OASL
Reactivity
Human
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA
Purity
Affinity Chromatography
Synonyms
2'; 5'-Oligoadenylate Synthetase; Polyclonal Antibody; Polyclonal Antibody to 2'; 5'-Oligoadenylate Synthetase Like Protein (OASL); anti-OASL antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody is a rabbit polyclonal antibody raised against OASL. It has beenselected for its ability to recognize OASL in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Liquid
Concentration
500ug/mL (varies by lot)
Sequence Length
514
Applicable Applications for anti-OASL antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes
Western blotting: 0.2-2ug/mL;1:250-2500
Immunohistochemistry: 5-20ug/mL;1:25-100
Immunocytochemistry: 5-20ug/mL;1:25-100
Optimal working dilutions must be determined by end user.
Immunohistochemistry: 5-20ug/mL;1:25-100
Immunocytochemistry: 5-20ug/mL;1:25-100
Optimal working dilutions must be determined by end user.
Fragment
OASL (Ala2~Trp244)
Organism Species
Homo sapiens (Human)
Cross Reactivity
Human
Conjugate
No Conjugate
Immunogen
Recombinant OASL (Ala2~Trp244) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2077033
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:HumanTissue))
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:HumanTissue))
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
43,942 Da
NCBI Official Full Name
2'-5'-oligoadenylate synthase-like protein isoform c
NCBI Official Synonym Full Names
2'-5'-oligoadenylate synthetase like
NCBI Official Symbol
OASL
NCBI Official Synonym Symbols
OASL1; OASLd; TRIP14; TRIP-14; p59OASL; p59 OASL; p59-OASL
NCBI Protein Information
2'-5'-oligoadenylate synthase-like protein
UniProt Protein Name
2'-5'-oligoadenylate synthase-like protein
Protein Family
UniProt Gene Name
OASL
UniProt Synonym Gene Names
TRIP14; 2'-5'-OAS-RP; TR-interacting protein 14; TRIP-14; p59OASL
Uniprot Description
OASL: a protein of the 2'-5'-oligoadenylate synthetase family, but does not have 2'-5'-OAS activity. Binds double-stranded RNA and DNA. Interacts with the ligand binding domain of the thyroid receptor (TR). Does not require the presence of thyroid hormone for its interaction. Contains a ubiquitin-like domain that interacts with methyl CpG-binding protein 1.
Protein type: DNA-binding; Nucleolus
Chromosomal Location of Human Ortholog: 12q24.31
Cellular Component: cytoplasm; cytosol; membrane; nucleolus; nucleoplasm
Molecular Function: 2'-5'-oligoadenylate synthetase activity; ATP binding; DNA binding; double-stranded RNA binding; RNA binding; thyroid hormone receptor binding
Biological Process: defense response to virus; negative regulation of viral genome replication; response to virus
Research Articles on OASL
Similar Products
Product Notes
The OASL oasl (Catalog #AAA2028787) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to 2',5'-Oligoadenylate Synthetase Like Protein (OASL) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's 2',5'-Oligoadenylate Synthetase can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.2-2ug/mL;1:250-2500 Immunohistochemistry: 5-20ug/mL;1:25-100 Immunocytochemistry: 5-20ug/mL;1:25-100 Optimal working dilutions must be determined by end user. . Researchers should empirically determine the suitability of the OASL oasl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "2',5'-Oligoadenylate Synthetase, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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