Chicken polymerase (RNA) III (DNA directed) polypeptide A, 155kDa ELISA Kit | POLR3A elisa kit

Chicken DNA-directed RNA polymerase III subunit RPC1, POLR3A ELISA Kit

• Reactivity: Chicken
• Synonyms: polymerase (RNA) III (DNA directed) polypeptide A; 155kDa; Chicken DNA-directed RNA polymerase III subunit RPC1; POLR3A ELISA Kit; Chicken DNA-directed RNA polymerase III subunit RPC1 (POLR3A) ELISA kit; RPC1; RPC155; hRPC155; RNA polymerase III subunit RPC155-D; POLR3A elisa kit

• Reactivity: Chicken

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 57529842
• NCBI GeneID: 423727
• NCBI Accession #: NP_001006500.1
• NCBI GenBank Nucleotide #: NM_001006500.1
• UniProt Accession #: Q5ZL98
• Molecular Weight: 155,704 Da
• NCBI Official Full Name: DNA-directed RNA polymerase III subunit RPC1
• NCBI Official Synonym Full Names: polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
• NCBI Official Symbol: POLR3A
• NCBI Protein Information: DNA-directed RNA polymerase III subunit RPC1; RNA polymerase III subunit C1; DNA-directed RNA polymerase III subunit A
• UniProt Protein Name: DNA-directed RNA polymerase III subunit RPC1
• UniProt Gene Name: POLR3A
• UniProt Synonym Gene Names: RCJMB04_7b9; RNA polymerase III subunit C1
• UniProt Entry Name: RPC1_CHICK

Uniprot Description

Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Forms the polymerase active center together with the second largest subunit. A single-stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol III. A bridging helix emanates from RPC1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol III by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition

Catalytic activity: Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).