Human Proteolipid protein 2 ELISA Kit | PLP2 elisa kit

Human Proteolipid protein 2 (PLP2) ELISA Kit

Cat. Num. AAA282391

• Gene Names: PLP2; A4; A4LSB
• Reactivity: Human
• Synonyms: Proteolipid protein 2; Human Proteolipid protein 2 (PLP2) ELISA Kit; PLP2 elisa kit

• Reactivity: Human
• Specificity: This assay has high sensitivity and excellent specificity for detection of Human PLP2. No significant cross-reactivity or interference between Human PLP2 and analogues was observed.
• Sequence Length: 152

• Samples: Serum, Plasma, Other biological fluids
• Assay Type: Sandwich
• Sample Volume: 1-200 uL
• Precision: Intra-assay Precision (Precision within an assay); Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.; Inter-assay Precision (Precision between assays); Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.; CV (%) = SD/meanX100; Intra-Assay: CV; Inter-Assay: CV
• Detection Wavelength: 450 nm
• Preparation and Storage: Store at 2-8 degree C.

Related Product Information for PLP2 elisa kit

Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate PLP2 in samples. An antibody specific for PLP2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyPLP2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PLP2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PLP2 bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

• NCBI GI #: 4505893
• NCBI GeneID: 5355
• NCBI Accession #: NP_002659.1
• NCBI GenBank Nucleotide #: NM_002668.2
• UniProt Accession #: Q04941; Q32MM8; A6NDT7
• Molecular Weight: 15,946 Da
• NCBI Official Full Name: proteolipid protein 2
• NCBI Official Synonym Full Names: proteolipid protein 2
• NCBI Official Symbol: PLP2
• NCBI Official Synonym Symbols: A4; A4LSB
• NCBI Protein Information: proteolipid protein 2
• UniProt Protein Name: Proteolipid protein 2
• Protein Family: Proteolipid protein
• UniProt Gene Name: PLP2
• UniProt Synonym Gene Names: A4

NCBI Description

This gene encodes an integral membrane protein that localizes to the endoplasmic reticulum in colonic epithelial cells. The encoded protein can multimerize and may function as an ion channel. A polymorphism in the promoter of this gene may be linked to an increased risk of X-linked cognitive disability. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Jan 2010]

Uniprot Description

PLP2: May play a role in cell differentiation in the intestinal epithelium. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell development/differentiation; Endoplasmic reticulum; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: Xp11.23

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral component of membrane; membrane; plasma membrane

Molecular Function: chemokine binding; ion transmembrane transporter activity; protein binding

Biological Process: chemotaxis; cytokine-mediated signaling pathway; ion transport