Perilipin-5 (Plin5) Recombinant Protein | Plin5 recombinant protein
Recombinant Sheep Perilipin-5 (Plin5)
NCBI and Uniprot Product Information
Uniprot Description
Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2. Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE ().
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Product Notes
The Plin5 plin5 (Catalog #AAA1236846) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-456, Full length protein. The amino acid sequence is listed below: MSEDEAAQAP GPSLSEQDQQ SAVQRVAALP LIRATCTAVS EAYSAAKDRH PLLGSACRLA EHCVCDLTTR ALDHAQPLLS HLQPQLATVN DLACRGLDKL EEKLPFLQQP SETVVTSAKG VVASSVTGMV GLARQGRRWS VELKRSVSHA MDVVLEKSEE LVDHFLPMTE EELAALAAEA EGPEVGSVEE QRKHQGYFVR LGSLSTRLRH LAYEHSLGKL RQKKHHAQDT LAQLQETLEL IHRMQCGVTP ITPARPGKVH ELWEDWSQRP LENGRRRHSQ AELETLVLSR NLMRELQSTV DALETSVRGL PPSAQEKVAE VRRSVDALQA AFADARRFGD LPAAVLAEGR GSMARAHACV DELLELVVQA MPLPWLVGPF APILVERPEP PPDLEALVDE VIGGPDPRWA HLDWPAQQRA WQAQHGEGTV LSGNIPEEEP EPPSRPKHTL MPELDF. It is sometimes possible for the material contained within the vial of "Perilipin-5 (Plin5), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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