Plant Integrin Alpha 2 Beta 1 (ITGA2B1) ELISA Kit | ITGA2B1 elisa kit
Plant Integrin Alpha 2 Beta 1 (ITGA2B1) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Uniprot Description
ITGA2: Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Belongs to the integrin alpha chain family.
Protein type: Membrane protein, integral; Cell adhesion; Receptor, misc.; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 5q11.2
Cellular Component: cell surface; focal adhesion; integrin complex; plasma membrane
Molecular Function: collagen binding; protein binding; protein complex binding
Biological Process: blood coagulation; cell adhesion; cell adhesion mediated by integrin; cell-matrix adhesion; cell-substrate adhesion; extracellular matrix organization and biogenesis; integrin-mediated signaling pathway; mesodermal cell differentiation; organ morphogenesis; substrate-bound cell migration
Disease: Bleeding Disorder, Platelet-type, 9
Research Articles on ITGA2B1
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Product Notes
The Plant ITGA2B1 itga2 (Catalog #AAA9377247) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9377247 ELISA Kit recognizes Plant ITGA2B1. It is sometimes possible for the material contained within the vial of "Integrin Alpha 2 Beta 1 (ITGA2B1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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