cAMP-dependent Protein Kinase Inhibitor beta/PKI-beta Recombinant Protein | PKI-beta recombinant protein
Recombinant Human cAMP-dependent Protein Kinase Inhibitor beta/PKI-beta Protein (N-6His)
Gene Names
PKIB; PRKACN2
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
cAMP-dependent Protein Kinase Inhibitor beta/PKI-beta; Recombinant Human cAMP-dependent Protein Kinase Inhibitor beta/PKI-beta Protein (N-6His); cAMP-Dependent Protein Kinase Inhibitor Beta; PKI-beta; PKIB; PRKACN2; PKI-beta recombinant protein
Host
E Coli
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Supplied as a 0.2 mum filtered solution of 20mM Tris HCl, 100mM NaCl, 1mM DTT, 20% Glycerol, pH 8.0.
Sequence Positions
Met1-Lys78
Sequence Length
78
Species
Human
Endotoxin
<1.0 EU per ug as determined by LAL test.
Fusion Tag
N-6His
Preparation and Storage
Store at < -20 degree C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Related Product Information for PKI-beta recombinant protein
cAMP-Dependent Protein Kinase Inhibitor beta (PKI-beta) is a member of the PKI family. As a member of the cAMP-dependent protein kinase inhibitor family, It has been shown that PKI-beta is an extremely potent competitive inhibitor of cAMP-dependent protein kinase activity; this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. It may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Molecular Mass: 10.6 kDa
Actual Protein Molecular Mass: 16 kDa
Actual Protein Molecular Mass: 16 kDa
NCBI Official Full Name
cAMP-dependent protein kinase inhibitor beta isoform 1
NCBI Official Synonym Full Names
cAMP-dependent protein kinase inhibitor beta
NCBI Official Symbol
PKIB
NCBI Official Synonym Symbols
PRKACN2
NCBI Protein Information
cAMP-dependent protein kinase inhibitor beta
UniProt Protein Name
cAMP-dependent protein kinase inhibitor beta
UniProt Gene Name
PKIB
UniProt Synonym Gene Names
PRKACN2; PKI-beta
NCBI Description
This gene encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Uniprot Description
Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.
Research Articles on PKI-beta
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Product Notes
The PKI-beta pkib (Catalog #AAA2552423) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Met1-Lys78. It is sometimes possible for the material contained within the vial of "cAMP-dependent Protein Kinase Inhibitor beta/PKI-beta, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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