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Bovine Polycystin-2 ELISA Kit | PKD2 elisa kit

Bovine Polycystin-2 ELISA Kit

Reactivity
Bovine
Synonyms
Polycystin-2; Bovine Polycystin-2 ELISA Kit; Polycystic kidney disease 2 protein homolog; PKD2; PKD2 elisa kit
Ordering
For Research Use Only!
Reactivity
Bovine
Sequence Length
970
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
109,789 Da
NCBI Official Full Name
polycystin-2
NCBI Official Symbol
PKD2
NCBI Protein Information
polycystin-2
UniProt Protein Name
Polycystin-2
Protein Family
UniProt Gene Name
PKD2
UniProt Entry Name
PKD2_BOVIN

Uniprot Description

Functions as a calcium permeable cation channel involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Together with TRPV4, forms mechano- and thermosensitive channels in cilium. PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. Acts as a regulator of cilium length, together with PKD1. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD1L1 in cilia to facilitate flow detection in left/right patterning.

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Product Notes

The Bovine PKD2 pkd2 (Catalog #AAA289921) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA289921 ELISA Kit recognizes Bovine PKD2. It is sometimes possible for the material contained within the vial of "Polycystin-2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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