Pigeon Homeobox A5 (HOXA5) ELISA Kit | HOXA5 elisa kit
Pigeon Homeobox A5 (HOXA5) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis. [provided by RefSeq, Jul 2008]
Uniprot Description
HOXA5: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Also binds to its own promoter. Binds specifically to the motif 5'-CYYNATTA[TG]Y-3'. Belongs to the Antp homeobox family.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 7p15.2
Cellular Component: nucleus
Molecular Function: DNA binding; protein binding; transcription factor activity
Biological Process: negative regulation of angiogenesis; negative regulation of erythrocyte differentiation; positive regulation of apoptosis; positive regulation of myeloid cell differentiation; positive regulation of transcription from RNA polymerase II promoter
Research Articles on HOXA5
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Product Notes
The Pigeon HOXA5 hoxa5 (Catalog #AAA9376299) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9376299 ELISA Kit recognizes Pigeon HOXA5. It is sometimes possible for the material contained within the vial of "Homeobox A5 (HOXA5), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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