Pyroglutamyl-Peptidase I Recombinant Protein | PGPEP1 recombinant protein
Recombinant Human Pyroglutamyl-Peptidase I
Gene Names
PGPEP1; PGP; Pcp; PGPI; PAP-I; PGP-I
Purity
Greater than 95.0% as determined by SDS-PAGE.
Synonyms
Pyroglutamyl-Peptidase I; Recombinant Human Pyroglutamyl-Peptidase I; PGPEP1 Human; Pyroglutamyl-Peptidase I Human Recombinant; Pyroglutamyl-peptidase 1; EC 3.4.19.3; 5-oxoprolyl-peptidase; Pyroglutamyl aminopeptidase I; PAP-I; Pyroglutamyl-peptidase I; PGP-I; Pyrrolidone-carboxylate peptidase; PGPEP1; PGPI; PGP; Pcp; PGPEP1 recombinant protein
Host
E Coli
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Form/Format
The PGPEP1 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT.
Sterile filtered colorless solution.
Sterile filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMEQPRKA VVVTGFGPFG EHTVNASWIA VQELEKLGLG DSVDLHVYEI PVEYQTVQRL IPALWEKHSP QLVVHVGVSG MATTVTLEKC GHNKGYKGLD NCRFCPGSQC CVEDGPESID SIIDMDAVCK RVTTLGLDVS VTISQDAGRY LCDFTYYTSL YQSHGRSAFV HVPPLGKPYN ADQLGRALRA IIEEMLDLLE QSEGKINYCH KH.
Sequence Length
111
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Related Product Information for PGPEP1 recombinant protein
PGPEP1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 232 amino acids (1-209) and having a molecular mass of 25.5kDa.PGPEP1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
pyroglutamyl-peptidase 1 isoform 2
NCBI Official Synonym Full Names
pyroglutamyl-peptidase I
NCBI Official Symbol
PGPEP1
NCBI Official Synonym Symbols
PGP; Pcp; PGPI; PAP-I; PGP-I
NCBI Protein Information
pyroglutamyl-peptidase 1; 5-oxoprolyl-peptidase; pyroglutamyl aminopeptidase I; pyrrolidone-carboxylate peptidase
UniProt Protein Name
Pyroglutamyl-peptidase 1
Protein Family
UniProt Gene Name
PGPEP1
UniProt Synonym Gene Names
PGPI; PAP-I; PGP-I
UniProt Entry Name
PGPI_HUMAN
NCBI Description
Pyroglutamyl peptidase I (EC 3.4.19.3) catalyzes the hydrolysis of N-terminal pyroglutamyl residues from oligopeptides and proteins.[supplied by OMIM, Mar 2008]
Uniprot Description
PGPEP1: Removes 5-oxoproline from various penultimate amino acid residues except L-proline. Belongs to the peptidase C15 family.
Protein type: EC 3.4.19.3; Protease
Chromosomal Location of Human Ortholog: 19p13.11
Cellular Component: cytosol
Molecular Function: pyroglutamyl-peptidase activity; cysteine-type peptidase activity
Biological Process: proteolysis
Research Articles on PGPEP1
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Product Notes
The PGPEP1 pgpep1 (Catalog #AAA146580) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSMEQ PRKA VVVTGFGPFG EHTVNASWIA VQELEKLGLG DSVDLHVYEI PVEYQTVQRL IPALWEKHSP QLVVHVGVSG MATTVTLEKC GHNKGYKGLD NCRFCPGSQC CVEDGPESID SIIDMDAVCK RVTTLGLDVS VTISQDAGRY LCDFTYYTSL YQSHGRSAFV HVPPLGKPYN ADQLGRALRA IIEEMLDLLE QSEGKINYCH KH.. It is sometimes possible for the material contained within the vial of "Pyroglutamyl-Peptidase I, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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