Poly-beta-1,6-N-acetyl-D-glucosamine synthase (pgaC) Recombinant Protein | pgaC recombinant protein
Recombinant Escherichia coli Poly-beta-1,6-N-acetyl-D-glucosamine synthase (pgaC)
NCBI and Uniprot Product Information
NCBI Description
PgaC complements a mutation in the homologous Y. pestis hemin storage gene hmsR. [More information is available at EcoGene: EG13863]. The pgaABCD locus is required for the synthesis of a cell-bound hexosamine-rich polysaccharide, which was identified as a linear polymer of beta-1,6-N-acetylglucosamine residues (PGA), an adhesin essential in biofilm formation . [More information is available at EcoCyc: G6529].
Uniprot Description
Function: Probable N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N-acetylglucosamine to produce the linear homopolymer poly-beta-1,6-N-acetyl-D-glucosamine (PGA), a biofilm adhesin polysaccharide. Ref.4 Ref.6
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Disruption phenotype: Cells lacking this gene do not synthesize PGA. Ref.4 Ref.6
Sequence similarities: Belongs to the glycosyltransferase 2 family.
Research Articles on pgaC
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Product Notes
The pgaC pgac (Catalog #AAA1147502) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-441. The amino acid sequence is listed below: MINRIVSFFI LCLVLCIPLC VAYFHSGELM MRFVFFWPFF MSIMWIVGGV YFWVYRERHW PWGENAPAPQ LKDNPSISII IPCFNEEKNV EETIHAALAQ RYENIEVIAV NDGSTDKTRA ILDRMAAQIP HLRVIHLAQN QGKAIALKTG AAAAKSEYLV CIDGDALLDR DAAAYIVEPM LYNPRVGAVT GNPRIRTRST LVGKIQVGEY SSIIGLIKRT QRIYGNVFTV SGVIAAFRRS ALAEVGYWSD DMITEDIDIS WKLQLNQWTI FYEPRALCWI LMPETLKGLW KQRLRWAQGG AEVFLKNMTR LWRKENFRMW PLFFEYCLTT IWAFTCLVGF IIYAVQLAGV PLNIELTHIA ATHTAGILLC TLCLLQFIVS LMIENRYEHN LTSSLFWIIW FPVIFWMLSL ATTLVSFTRV MLMPKKQRAR WVSPDRGILR G. It is sometimes possible for the material contained within the vial of "Poly-beta-1,6-N-acetyl-D-glucosamine synthase (pgaC), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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