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Arachis hypogaea Lectin

Arachis hypogaea (PNA, Peanut Agglutinin) (FITC)

Applications
Immunohistochemistry
Purity
Molecular Biology Grade
Synonyms
Arachis hypogaea; Arachis hypogaea (PNA; Peanut Agglutinin) (FITC); Arachis hypogaea lectin
Ordering
For Research Use Only!
Host
Peanut
Purity/Purification
Molecular Biology Grade
Form/Format
Supplied as a liquid in 0.02M sodium bicarbonate, pH 9.3, 0.05% sodium azide. Labeled with fluorescein isothiocyanate (FITC).
Applicable Applications for Arachis hypogaea lectin
Immunohistochemistry (IHC)
Activity
<1ug/ml will agglutinate human erythrocytes neuraminidase treatment of the cells.
Carbohydrate Specificity
Terminal b-Galactose
Inhibitory Carbohydrate
Lactose > b-Galactose.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. FITC conjugates are sensitive to light.
Related Product Information for Arachis hypogaea lectin
Lectins are derived from the extracts of plants, animals, viruses and microorganisms and are known to agglutinate red blood cells. These agglutinins can select cell types according to blood group activities utilizing sugar-binding mechanisms.

Lectins form precipitates with glycoconjugates and are useful for identifying or separating oligosaccharides with identical sugar compositions such as galactose, mannose or glucose.
Arachis hypogaea (PNA, Peanut Agglutinin), 110kD, is composed of four identical subunits of approximately 27kD each, is galactose-specific, with strong anti-T-antigen activity. T-antigen") is present in many glycoconjugates such as M and N blood groups, gangliosides, and many other soluble and membrane-associated glycoproteins and glycolipids. PNA does not agglutinate normal human erythrocytes, but strongly agglutinates neuraminidase-treated red blood cells. The presence of Ca++ can enhance the binding of PNA to receptors. Asialo GM1 ganglioside is also thought to be a major cell surface receptor for PNA. PNA is useful in normal and tumor tissue determination for transitional mucosa malignancies.
Product Categories/Family for Arachis hypogaea lectin

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Product Notes

The Arachis hypogaea (Catalog #AAA655853) is a Lectin produced from Peanut and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Arachis hypogaea can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the Arachis hypogaea for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Arachis hypogaea, Lectin" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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