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Phosducin-Like 3 Recombinant Protein | PDCL3 recombinant protein

Recombinant Human Phosducin-Like 3

Gene Names
PDCL3; VIAF; PHLP3; VIAF1; HTPHLP; PHLP2A
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
Phosducin-Like 3; Recombinant Human Phosducin-Like 3; PDCL3 Human; Phosducin-Like 3 Human Recombinant; Phosducin-like protein 3; VIAF1; Viral IAP-associated factor 1; HTPHLP; VIAF-1; PHLP3; PHLP2A; IAP-associated factor VIAF1; PDCL3 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
The PDCL3 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 100mM NaCl and 10% glycerol.
Sterile Filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMQDPNAD TEWNDILRKK GILPPKESLK ELEEEAEEEQ RILQQSVVKT YEDMTLEELE DHEDEFNEED ERAIEMYRRR RLAEWKATKL KNKFGEVLEI SGKDYVQEVT KAGEGLWVIL HLYKQGIPLC ALINQHLSGL ARKFPDVKFI KAISTTCIPN YPDRNLPTIF VYLEGDIKAQ FIGPLVFGGM NLTRDELEWK LSESGAIMTD LEENPKKPIE DVLLSSVRRS VLMKRDSDSE GD.
Sequence Length
239
Related Product Information for PDCL3 recombinant protein
Description: PDCL3 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 262 amino acids (1-239) and having a molecular mass of 30.0kDa.PDCL3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Introduction: PDCL3 belongs to the phosducin-like protein family which its members are known to bind to the beta-gamma subunits of G proteins. PDCL3 is a potential regulator of heterotrimeric G proteins and has a large amino acid sequence homology with phosducin.
Product Categories/Family for PDCL3 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
27,614 Da
NCBI Official Full Name
phosducin-like protein 3
NCBI Official Synonym Full Names
phosducin-like 3
NCBI Official Symbol
PDCL3
NCBI Official Synonym Symbols
VIAF; PHLP3; VIAF1; HTPHLP; PHLP2A
NCBI Protein Information
phosducin-like protein 3; IAP-associated factor VIAF1; VIAF-1; phPL3; viral IAP-associated factor 1
UniProt Protein Name
Phosducin-like protein 3
Protein Family
UniProt Gene Name
PDCL3
UniProt Synonym Gene Names
PhLP2A; VIAF1; VIAF-1
UniProt Entry Name
PDCL3_HUMAN

NCBI Description

This gene encodes a member of the phosducin-like protein family and is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin. Members of the phosducin-like protein family have been shown to bind to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008]

Uniprot Description

PDCL3: Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination. Belongs to the phosducin family.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 2q11.2

Cellular Component: cytoplasm

Molecular Function: protein binding; vascular endothelial growth factor receptor 2 binding

Biological Process: positive regulation of angiogenesis; protein folding; viral reproduction; apoptosis; positive regulation of endothelial cell proliferation; angiogenesis; regulation of peptidyl-tyrosine phosphorylation

Research Articles on PDCL3

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Product Notes

The PDCL3 pdcl3 (Catalog #AAA144907) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSMQD PNAD TEWNDILRKK GILPPKESLK ELEEEAEEEQ RILQQSVVKT YEDMTLEELE DHEDEFNEED ERAIEMYRRR RLAEWKATKL KNKFGEVLEI SGKDYVQEVT KAGEGLWVIL HLYKQGIPLC ALINQHLSGL ARKFPDVKFI KAISTTCIPN YPDRNLPTIF VYLEGDIKAQ FIGPLVFGGM NLTRDELEWK LSESGAIMTD LEENPKKPIE DVLLSSVRRS VLMKRDSDSE GD. It is sometimes possible for the material contained within the vial of "Phosducin-Like 3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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