NCBI Description
This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus. [provided by RefSeq, Jul 2008]
Uniprot Description
PARP4: Component of the vault ribonucleoprotein particle, at least composed of MVP, PARP4 and one or more vault RNAs (vRNAs). Binds to MVP. Associates with TEP1.
Protein type: EC 2.4.2.30; Transferase
Chromosomal Location of Human Ortholog: 13q11
Cellular Component: membrane; spindle microtubule; cytoplasm; nucleus; ribonucleoprotein complex
Molecular Function: protein binding; enzyme binding; DNA binding; NAD+ ADP-ribosyltransferase activity
Biological Process: response to drug; cell death; protein amino acid ADP-ribosylation; transport; protein modification process; inflammatory response; DNA repair; response to DNA damage stimulus
Product Notes
The Mouse PARP4 parp4 (Catalog #
AAA053506) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA053506 ELISA Kit recognizes Mouse PARP4.
It is sometimes possible for the material contained within the vial of
"Poly ADP Ribose Polymerase 4, ELISA Kit" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are
absolutely not suitable for use in any
sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a
product from AAA Biotech, you
are explicitly certifying that said products will be properly tested and used in line with
industry standard. AAA Biotech
and its authorized distribution partners reserve the right to refuse to fulfill any order if
we have any indication that a
purchaser may be intending to use a product outside of our accepted criteria.
Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech
cannot be held
responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any
aspect of this datasheet at
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of any product performance
issues observed or experienced within 30 days of receipt of said product. To see additional
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