Cat Pappalysin 2 ELISA Kit | PAPPA2 elisa kit

Cat Pappalysin 2 ELISA Kit

• Gene Names: PAPPA2; PAPPE; PLAC3; PAPP-E; PAPP-A2
• Reactivity: Cat
• Synonyms: Pappalysin 2; Cat Pappalysin 2 ELISA Kit; PAPPA2 elisa kit

• Reactivity: Cat

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 116174738
• NCBI GeneID: 60676
• NCBI Accession #: NP_064714.2
• NCBI GenBank Nucleotide #: NM_020318.2
• UniProt Accession #: Q9BXP8; Q96PH7; Q96PH8; Q9H4C9; A9Z1Y8
• Molecular Weight: 198,539 Da
• NCBI Official Full Name: pappalysin-2 isoform 1
• NCBI Official Synonym Full Names: pappalysin 2
• NCBI Official Symbol: PAPPA2
• NCBI Official Synonym Symbols: PAPPE; PLAC3; PAPP-E; PAPP-A2
• NCBI Protein Information: pappalysin-2; placenta-specific 3; pregnancy-associated plasma protein E1; pregnancy-associated plasma preproprotein-A2
• UniProt Protein Name: Pappalysin-2
• Protein Family: Pappalysin
• UniProt Gene Name: PAPPA2
• UniProt Synonym Gene Names: PLAC3; PAPP-A2; PAPP-E
• UniProt Entry Name: PAPP2_HUMAN

NCBI Description

This gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin-like growth factor-binding protein 5 and is thought to be a local regulator of insulin-like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]

Uniprot Description

PAPPA2: Metalloproteinase which specifically cleaves IGFBP-5. Shows limited proteolysis toward IGFBP-3. Belongs to the peptidase M43B family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protease; Secreted; EC 3.4.24.-; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1q25.2

Cellular Component: membrane; extracellular region; intracellular

Molecular Function: metallopeptidase activity; zinc ion binding

Biological Process: cellular protein metabolic process; regulation of cell growth; cell differentiation; proteolysis