Uniprot Description
Function: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors
By similarity. HAMAP-Rule MF_03172
Catalytic activity: ATP + (d)CMP = ADP + (d)CDP. HAMAP-Rule MF_03172ATP + UMP = ADP + UDP. HAMAP-Rule MF_03172
Cofactor: Binds 1 magnesium ion per monomer
By similarity. HAMAP-Rule MF_03172
Subunit structure: Monomer
By similarity. HAMAP-Rule MF_03172
Subcellular location: Cytoplasm
By similarity. Nucleus
By similarity HAMAP-Rule MF_03172.
Domain: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis
By similarity. HAMAP-Rule MF_03172
Sequence similarities: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
Sequence caution: The sequence CAB75933.1 differs from that shown. Reason: Erroneous gene model prediction.
Product Notes
The Pigeon P-CK ck (Catalog #
AAA079861) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA079861 ELISA Kit recognizes Pigeon P-CK.
It is sometimes possible for the material contained within the vial of
"Pan-Cytokeratin, ELISA Kit" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are
absolutely not suitable for use in any
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and its authorized distribution partners reserve the right to refuse to fulfill any order if
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purchaser may be intending to use a product outside of our accepted criteria.
Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech
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responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any
aspect of this datasheet at
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of any product performance
issues observed or experienced within 30 days of receipt of said product. To see additional
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