3-Oxoacyl-ACP Synthase Recombinant Protein | OXSM recombinant protein
Recombinant Human 3-Oxoacyl-ACP Synthase, Mitochondrial
Gene Names
OXSM; KS; KASI; FASN2D
Purity
Greater than 90.0% as determined by SDS-PAGE.
Synonyms
3-Oxoacyl-ACP Synthase; Recombinant Human 3-Oxoacyl-ACP Synthase; Mitochondrial; OXSM Human; Mitochondrial Human Recombinant; 3-Oxoacyl-ACP Synthase Mitochondrial; Type II Mitochondrial Beta-Ketoacyl Synthase; 3-Ketoacyl-Acyl Carrier Protein Synthase; FASN2D; KASI; EC 2.3.1; Beta-Ketoacyl-ACP Synthase; OXSM recombinant protein
Host
E Coli
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Form/Format
The OXSM solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 0.15M NaCl, 1mM DTT and 10% glycerol.
Sterile Filtered clear solution.
Sterile Filtered clear solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSKRKFFGT VPISRLHRRV VITGIGLVTP LGVGTHLVWD RLIGGESGIV SLVGEEYKSI PCSVAAYVPR GSDEGQFNEQ NFVSKSDIKS MSSPTIMAIG AAELAMKDSG WHPQSEADQV ATGVAIGMGM IPLEVVSETA LNFQTKGYNK VSPFFVPKIL VNMAAGQVSI RYKLKGPNHA VSTACTTGAH AVGDSFRFIA HGDADVMVAG GTDSCISPLS LAGFSRARAL STNSDPKLAC RPFHPKRDGF VMGEGAAVLV LEEYEHAVQR RARIYAEVLG YGLSGDAGHI TAPDPEGEGA LRCMAAALKD AGVQPEEISY INAHATSTPL GDAAENKAIK HLFKDHAYAL AVSSTKGATG HLLGAAGAVE AAFTTLACYY QKLPPTLNLD CSEPEFDLNY VPLKAQEWKT EKRFIGLTNS FGFGGTNATL CIAGL.
Sequence Length
376
Related Product Information for OXSM recombinant protein
Description: OXSM Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 455 amino acids (28-459) and having a molecular mass of 48.1kDa.OXSM is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: OXSM, a beta-ketoacyl synthetase, is essential for elongation of fatty acid chains in the mitochondria. Alternatively spliced transcript variants were found.
Introduction: OXSM, a beta-ketoacyl synthetase, is essential for elongation of fatty acid chains in the mitochondria. Alternatively spliced transcript variants were found.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
40,035 Da
NCBI Official Full Name
3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial isoform 2
NCBI Official Synonym Full Names
3-oxoacyl-ACP synthase, mitochondrial
NCBI Official Symbol
OXSM
NCBI Official Synonym Symbols
KS; KASI; FASN2D
NCBI Protein Information
3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; 3-ketoacyl-acyl carrier protein synthase; 3-oxoacyl-acyl-carrier-protein synthase; acyl-malonyl acyl carrier protein-condensing enzyme; beta-ketoacyl synthase; beta-ketoacyl-ACP synthase; type II mitochondrial beta-ketoacyl synthase
UniProt Protein Name
3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial
Protein Family
UniProt Gene Name
OXSM
UniProt Entry Name
OXSM_HUMAN
NCBI Description
This gene encodes a beta-ketoacyl synthetase. The encoded enzyme is required for elongation of fatty acid chains in the mitochondria. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2009]
Uniprot Description
OXSM: May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the beta-ketoacyl-ACP synthases family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transferase; EC 2.3.1.41; Lipid Metabolism - fatty acid biosynthesis; Mitochondrial
Chromosomal Location of Human Ortholog: 3p24.2
Cellular Component: mitochondrion; cytoplasm
Molecular Function: 3-oxoacyl-[acyl-carrier-protein] synthase activity
Biological Process: medium-chain fatty acid biosynthetic process; acyl-CoA metabolic process; short-chain fatty acid biosynthetic process
Research Articles on OXSM
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Product Notes
The OXSM oxsm (Catalog #AAA146358) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSKRK FFGT VPISRLHRRV VITGIGLVTP LGVGTHLVWD RLIGGESGIV SLVGEEYKSI PCSVAAYVPR GSDEGQFNEQ NFVSKSDIKS MSSPTIMAIG AAELAMKDSG WHPQSEADQV ATGVAIGMGM IPLEVVSETA LNFQTKGYNK VSPFFVPKIL VNMAAGQVSI RYKLKGPNHA VSTACTTGAH AVGDSFRFIA HGDADVMVAG GTDSCISPLS LAGFSRARAL STNSDPKLAC RPFHPKRDGF VMGEGAAVLV LEEYEHAVQR RARIYAEVLG YGLSGDAGHI TAPDPEGEGA LRCMAAALKD AGVQPEEISY INAHATSTPL GDAAENKAIK HLFKDHAYAL AVSSTKGATG HLLGAAGAVE AAFTTLACYY QKLPPTLNLD CSEPEFDLNY VPLKAQEWKT EKRFIGLTNS FGFGGTNATL CIAGL. It is sometimes possible for the material contained within the vial of "3-Oxoacyl-ACP Synthase, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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