Odorant receptor 43a (Or43a) Recombinant Protein | Or43a recombinant protein
Recombinant Drosophila melanogaster Odorant receptor 43a (Or43a)
NCBI and Uniprot Product Information
Uniprot Description
Function: Complexes with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability. They are necessary and sufficient to promote functional reconstitution of odor-evoked signaling in sensory neurons that normally respond only to carbon dioxide. Ref.6
Subunit structure: Interacts with Orco. Complexes exist early in the endomembrane system in olfactory sensory neurons (OSNs), coupling these complexes to the conserved ciliary trafficking pathway. Ref.6
Subcellular location: Cell membrane; Multi-pass membrane protein
By similarity.
Tissue specificity: Expressed with Orco in 20 sensory neurons on the distal edge of the antenna. Ref.1 Ref.5 Ref.6
Miscellaneous: The atypical heteromeric and topological design of the odorant receptors appears to be an insect-specific solution for odor recognition, making the OR/Orco complex an attractive target for the development of highly selective insect repellents to disrupt olfactory-mediated host-seeking behaviors of insect disease vectors. Odor-evoked OR currents are independent of known G-protein-coupled second messenger pathways.
Sequence similarities: Belongs to the heteromeric odorant receptor channel (TC 1.A.69) family. [View classification]
Research Articles on Or43a
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Product Notes
The Or43a or43a (Catalog #AAA1192715) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-376. The amino acid sequence is listed below: MTIEDIGLVG INVRMWRHLA VLYPTPGSSW RKFAFVLPVT AMNLMQFVYL LRMWGDLPAF ILNMFFFSAI FNALMRTWLV IIKRRQFEEF LGQLATLFHS ILDSTDEWGR GILRRAEREA RNLAILNLSA SFLDIVGALV SPLFREERAH PFGLALPGVS MTSSPVYEVI YLAQLPTPLL LSMMYMPFVS LFAGLAIFGK AMLQILVHRL GQIGGEEQSE EERFQRLASC IAYHTQVMRY VWQLNKLVAN IVAVEAIIFG SIICSLLFCL NIITSPTQVI SIVMYILTML YVLFTYYNRA NEICLENNRV AEAVYNVPWY EAGTRFRKTL LIFLMQTQHP MEIRVGNVYP MTLAMFQSLL NASYSYFTML RGVTGK. It is sometimes possible for the material contained within the vial of "Odorant receptor 43a (Or43a), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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