2-oxoglutarate dehydrogenase Recombinant Protein | Ogdh recombinant protein
Recombinant Mouse 2-oxoglutarate dehydrogenase, mitochondrial
Gene Names
Ogdh; d1401; AA409584; mKIAA4192; 2210403E04Rik; 2210412K19Rik
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
2-oxoglutarate dehydrogenase; Recombinant Mouse 2-oxoglutarate dehydrogenase; mitochondrial ; 2-oxoglutarate dehydrogenase complex component E1; OGDC-E1; Alpha-ketoglutarate dehydrogenase; Ogdh recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
695-1023aa; Partial
Sequence
VDKRTCIPMNHLWPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFNNMAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPDLQEENFDINQLYDCNWIVVNCSTPGNFFHVLRRQILLPFRKPLIVFTPKSLLRHPEARTSFDEMLPGTHFQRVIPENGPAAQDPHKVKRLLFCTGKVYYDLTRERKARNMEEEVAITRIEQLSPFPFDLLLKEAQKYPNAELAWCQEEHKNQGYYDYVKPRLRTTIDRAKPVWYAGRDPAAAPATGNKKTHLTELQRFLDTAFDLDAFKKFS
Species
Mus musculus (Mouse)
Production Note
Special Offer: The E Coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Colihost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to support@mybiosource.com for more details.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
SDS-PAGE
Related Product Information for Ogdh recombinant protein
The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).
Product Categories/Family for Ogdh recombinant protein
References
"Prediction of the coding sequences of mouse homologues of KIAA gene. The complete nucleotide sequences of mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
Okazaki N., Kikuno R.F., Ohara R., Inamoto S., Nagase T., Ohara O., Koga H.
Submitted (FEB-2005)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
53.9 kDa
NCBI Official Full Name
2-oxoglutarate dehydrogenase, mitochondrial isoform 1
NCBI Official Synonym Full Names
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
NCBI Official Symbol
Ogdh
NCBI Official Synonym Symbols
d1401; AA409584; mKIAA4192; 2210403E04Rik; 2210412K19Rik
NCBI Protein Information
2-oxoglutarate dehydrogenase, mitochondrial
UniProt Protein Name
2-oxoglutarate dehydrogenase, mitochondrial
Protein Family
UniProt Gene Name
Ogdh
UniProt Synonym Gene Names
Kiaa4192; OGDC-E1
UniProt Entry Name
ODO1_MOUSE
Uniprot Description
OGDH: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the alpha-ketoglutarate dehydrogenase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Amino Acid Metabolism - lysine degradation; Amino Acid Metabolism - tryptophan; Carbohydrate Metabolism - citrate (TCA) cycle; Mitochondrial; Oxidoreductase; EC 1.2.4.2
Cellular Component: mitochondrion; oxoglutarate dehydrogenase complex
Molecular Function: chaperone binding; heat shock protein binding; metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; oxoglutarate dehydrogenase (succinyl-transferring) activity; thiamin pyrophosphate binding
Biological Process: 2-oxoglutarate metabolic process; glycolysis; metabolic process; NADH metabolic process; succinyl-CoA metabolic process; tricarboxylic acid cycle
