Typical Testing Data/Standard Curve (for reference only)
(Human Oncomodulin PicoKine ELISA Kit standard curve )
Human Oncomodulin ELISA Kit | OCM elisa kit
Human Oncomodulin PicoKine ELISA Kit
Gene Names
OCM; OM; OCM1; ONCM
Reactivity
Human
Synonyms
Oncomodulin; Human Oncomodulin PicoKine ELISA Kit; Ocm; OCMN; OCM1; OM; onco; Oncomodulin-1; Oncomodulin 1; Parvalbumin beta; P0CE72; oncomodulin; OCM elisa kit
Reactivity
Human
Specificity
Natural and recombinant Human Oncomodulin
Sequence Length
109
Samples
Cell culture supernates, serum and plasma(heparin, EDTA).
Assay Type
Sandwich
Detection Range
31.2pg/ml-2000pg/ml
Sensitivity
<10pg/ml
Intra-assay Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision.
Inter-assay Precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision.
Preparation and Storage
Store at 4 degree C for 6 months, at -20 degree C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice).
Typical Testing Data/Standard Curve (for reference only)
(Human Oncomodulin PicoKine ELISA Kit standard curve )
Typical Testing Data/Standard Curve (for reference only)
(Human Oncomodulin PicoKine ELISA Kit standard curve )
Related Product Information for OCM elisa kit
Principle of the Assay: Human Oncomodulin ELISA Kit was based on standard sandwich enzyme-linked immunesorbent assay technology. A monoclonal antibody from mouse specific for Oncomodulin has been precoated onto 96-well plates. Standards(Expression system for standard: E.coli; Immunogen sequence: S2-S109) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for Oncomodulin is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the Human Oncomodulin amount of sample captured in plate.
Background/Introduction: Oncomodulin, also known as OCM, is an oncodevelopmental protein found in early embryonic cells in the placenta and also in tumors. The human gene for oncomodulin is located on chromosome 7. It is a parvalbumin- family calcium-binding protein expressed and secreted by macrophages that typically traffic to tissue as an inflammatory response or after injury. Oncomodulin promotes axon regeneration in retinal ganglion cells and maintains functioning in mouse cochlear hair cells.
Background/Introduction: Oncomodulin, also known as OCM, is an oncodevelopmental protein found in early embryonic cells in the placenta and also in tumors. The human gene for oncomodulin is located on chromosome 7. It is a parvalbumin- family calcium-binding protein expressed and secreted by macrophages that typically traffic to tissue as an inflammatory response or after injury. Oncomodulin promotes axon regeneration in retinal ganglion cells and maintains functioning in mouse cochlear hair cells.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
12,184 Da
NCBI Official Full Name
oncomodulin-1
NCBI Official Synonym Full Names
oncomodulin
NCBI Official Symbol
OCM
NCBI Official Synonym Symbols
OM; OCM1; ONCM
NCBI Protein Information
oncomodulin-1
UniProt Protein Name
Oncomodulin-1
Protein Family
UniProt Gene Name
OCM
UniProt Synonym Gene Names
OCM1; OCMN; OM
UniProt Entry Name
ONCO_HUMAN
NCBI Description
Oncomodulin is a high-affinity calcium ion-binding protein. It belongs to the superfamily of calmodulin proteins, also known as the EF-hand proteins. Oncomodulin is an oncodevelopmental protein found in early embryonic cells in the placenta and also in tumors. [provided by RefSeq, Jul 2008]
Uniprot Description
OCM: Has some calmodulin-like activity with respect to enzyme activation and growth regulation. Binds two calcium ions. Belongs to the parvalbumin family.
Chromosomal Location of Human Ortholog: 7p22.1
Research Articles on OCM
1. Deletion of oncomodulin in outer hair cells, leads to a progressive hearing loss in transgenic mice.
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Product Notes
The Human OCM ocm (Catalog #AAA178574) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA178574 ELISA Kit recognizes Human OCM. It is sometimes possible for the material contained within the vial of "Oncomodulin, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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