Neurexophilin 1 Recombinant Protein | NXPH1 recombinant protein

Recombinant Neurexophilin 1 (NXPH1)

Cat. Num. AAA2030984

• Gene Names: NXPH1; NPH1; Nbla00697
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: >90%
• Synonyms: Neurexophilin 1; Recombinant Neurexophilin 1 (NXPH1); NXPH1 recombinant protein

• Host: Host: E Coli; Source: Prokaryotic expression
• Purity/Purification: >90%
• Form/Format: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Sequence: The target protein is fused with two N-terminal Tags, His-tag and GST-tag, its sequence is listed below.; ANLTNGGKS ELLKSGSSKS TLKHIWTESSKDLSISRLLS QTFRGKENDT DLDLRYDTPE PYSEQDLWDW LRNSTDLQEPRPRAKRRPIV KTGKFKKMFG WGDFHSNIKT VKLNLLITGK IVDHGNGTFSVYFRHNSTGQ GNVSVSLVPP TKIVEFDLAQ QTVIDAKDSK SFNCRIEYEKVDKATKNTLC NYDPSKTCYQ EQTQSHVSWL CSKPFKVICI YISFYSTDYKLVQKVCPDYN YHSDTPYFPS G
• Sequence Length: 271

• Applicable Applications for NXPH1 recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Predicted Molecular Mass: 58.6kDa
• Accurate Molecular Mass (KD): 59kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Expression System: Prokaryotic expression
• Tag: two N-terminal Tags, His-tag and GST-tag
• Organism Species: Homo sapiens (Human)
• Fragment: Ala22~Gly271
• Usage: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 23097338
• NCBI GeneID: 30010
• NCBI Accession #: NP_689958.1
• NCBI GenBank Nucleotide #: NM_152745.2
• Molecular Weight: 31,082 Da
• NCBI Official Full Name: neurexophilin-1
• NCBI Official Synonym Full Names: neurexophilin 1
• NCBI Official Symbol: NXPH1
• NCBI Official Synonym Symbols: NPH1; Nbla00697
• NCBI Protein Information: neurexophilin-1
• UniProt Protein Name: Neurexophilin-1
• Protein Family: Neurexophilin
• UniProt Gene Name: NXPH1
• UniProt Synonym Gene Names: NPH1
• UniProt Entry Name: NXPH1_HUMAN

NCBI Description

This gene is a member of the neurexophilin family and encodes a secreted protein with a variable N-terminal domain, a highly conserved, N-glycosylated central domain, a short linker region, and a cysteine-rich C-terminal domain. This protein forms a very tight complex with alpha neurexins, a group of proteins that promote adhesion between dendrites and axons. [provided by RefSeq, Jul 2008]

Uniprot Description

NXPH1: May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors (Potential). Belongs to the neurexophilin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 7p22

Cellular Component: extracellular region

Molecular Function: receptor binding