Human nucleoporin 88kDa ELISA Kit | NUP88 elisa kit
Human Nuclear pore complex protein Nup88, NUP88 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias. [provided by RefSeq, Jul 2008]
Uniprot Description
NUP88: Essential component of nuclear pore complex.
Protein type: Nucleoporin; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 17p13.2
Cellular Component: nucleoplasm; nuclear pore; cytosol
Molecular Function: transporter activity
Biological Process: mRNA transport; viral reproduction; cytokine and chemokine mediated signaling pathway; mitotic nuclear envelope disassembly; pathogenesis; viral infectious cycle; glucose transport; protein transport; hexose transport; carbohydrate metabolic process; gene expression; viral transcription; mitotic cell cycle; transmembrane transport