Mouse Netrin-1 ELISA Kit | NTN1 elisa kit

Mouse Netrin-1 ELISA Kit

Cat. Num. AAA29930

• Gene Names: NTN1; NTN1L
• Reactivity: Mouse
• Synonyms: Netrin-1; Mouse Netrin-1 ELISA Kit; NTN1 elisa kit

• Reactivity: Mouse

• Sensitivity: 1.0 pg/ml.
• Preparation and Storage: Store all reagents at 2-8 degree C

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for NTN1 elisa kit

INTRODUCTION ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample.

INTENDED USE This ELISA kit is intended for laboratory in vitro research use only, not for drug, household or other use! The Stop Solution changes thecolor from blue to yellow and the intensity of the color is measured at 450 nm by a spectrophotometer. In order to measure the concentration of Mouse NTN1 in the sample, this ELISA kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versus Mouse NTN1 concentration. The concentration of Mouse NTN1 in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 148613884
• NCBI GeneID: 9423
• NCBI Accession #: NP_004813.2
• NCBI GenBank Nucleotide #: NM_004822.2
• UniProt Accession #: O95631; E9KL51
• Molecular Weight: 67,748 Da
• NCBI Official Full Name: netrin-1
• NCBI Official Synonym Full Names: netrin 1
• NCBI Official Symbol: NTN1
• NCBI Official Synonym Symbols: NTN1L
• NCBI Protein Information: netrin-1; netrin 1, mouse, homolog of; epididymis tissue protein Li 131P
• UniProt Protein Name: Netrin-1
• Protein Family: Netrin
• UniProt Gene Name: NTN1
• UniProt Synonym Gene Names: NTN1L
• UniProt Entry Name: NET1_HUMAN

NCBI Description

Netrin is included in a family of laminin-related secreted proteins. The function of this gene has not yet been defined; however, netrin is thought to be involved in axon guidance and cell migration during development. Mutations and loss of expression of netrin suggest that variation in netrin may be involved in cancer development. [provided by RefSeq, Jul 2008]

Uniprot Description

NTN1: Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: cytoplasm; extracellular region; basement membrane

Molecular Function: protein binding

Biological Process: axon guidance; cell-cell adhesion; inner ear morphogenesis; establishment of nucleus localization; apoptosis; positive regulation of axon extension; positive regulation of cell proliferation; neuron migration; negative regulation of axon extension; regulation of cell migration; anterior/posterior axon guidance