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Typical Testing Data/Standard Curve (for reference only)

Mouse Protein FAN ELISA Kit | Nsmaf elisa kit

Mouse Protein FAN ELISA Kit

Gene Names
NSMAF; FAN; GRAMD5
Reactivity
Mouse
Synonyms
Protein FAN; Mouse Protein FAN ELISA Kit; Factor associated with neutral sphingomyelinase activation; Factor associated with N-SMase activation; Nsmaf; Fan; Nsmaf elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Sequence Length
948
Assay Type
Sandwich
Detection Range
78-5000 pg/ml
Sensitivity
39.8 pg/mL
Intra-Assay CV
<=8.8%
Inter-Assay CV
<=11.2%
Recovery
93%
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
107,314 Da
NCBI Official Full Name
protein FAN isoform 2
NCBI Official Synonym Full Names
neutral sphingomyelinase activation associated factor
NCBI Official Symbol
NSMAF
NCBI Official Synonym Symbols
FAN; GRAMD5
NCBI Protein Information
protein FAN
UniProt Protein Name
Protein FAN
Protein Family
UniProt Gene Name
NSMAF
UniProt Synonym Gene Names
FAN; Factor associated with N-SMase activation
UniProt Entry Name
FAN_HUMAN

NCBI Description

This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]

Uniprot Description

NSMAF: Couples the p55 TNF-receptor (TNF-R55 / TNFR1) to neutral sphingomyelinase (N-SMASE). Specifically binds to the N- smase activation domain of TNF-R55. May regulate ceramide production by N-SMASE. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold; Autophagy

Chromosomal Location of Human Ortholog: 8q12-q13

Cellular Component: cytoplasm; cytosol; endomembrane system; extrinsic to membrane

Molecular Function: phospholipid binding; protein binding; receptor signaling protein activity

Biological Process: ceramide metabolic process; signal transduction

Research Articles on Nsmaf

Similar Products

Product Notes

The Mouse Nsmaf nsmaf (Catalog #AAA2888012) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2888012 ELISA Kit recognizes Mouse Nsmaf. It is sometimes possible for the material contained within the vial of "Protein FAN, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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