Genome polyprotein Recombinant Protein | flavivirus polyprotein gene recombinant protein
Recombinant West Nile virus Genome polyprotein, partial
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Genome polyprotein; Recombinant West Nile virus Genome polyprotein; partial; flavivirus polyprotein gene recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2526-3430
Sequence
GGAKGRTLGEVWKERLNHMTKEEFTRYRKEAITEVDRSAAKHARREGNITGGHPVSRGTAKLRWLVERRFLEPVGKVVDLGCGRGGWCYYMATQKRVQEVKGYTKGGPGHEEPQLVQSYGWNIVTMKSGVDVFYRPSEASDTLLCDIGESSSSAEVEEHRTVRVLEMVEDWLHRGPKEFCIKVLCPYMPKVIEKMETLQRRYGGGLIRNPLSRNSTHEMYWVSHASGNIVHSVNMTSQVLLGRMEKKTWKGPQFEEDVNLGSGTRAVGKPLLNSDTSKIKNRIERLKKEYSSTWHQDANHPYRTWNYHGSYEVKPTGSASSLVNGVVRLLSKPWDTITNVTTMAMTDTTPFGQQRVFKEKVDTKAPEPPEGVKYVLNETTNWLWAFLARDKKPRMCSREEFIGKVNSNAALGAMFEEQNQWKNAREAVEDPKFWEMVDEEREAHLRGECNTCIYNMMGKREKKPGEFGKAKGSRAIWFMWLGARFLEFEALGFLNEDHWLGRKNSGGGVEGLGLQKLGYILKEVGTKPGGKVYADDTAGWDTRITKADLENEAKVLELLDGEHRRLARSIIELTYRHKVVKVMRPAADGKTVMDVISREDQRGSGQVVTYALNTFTNLAVQLVRMMEGEGVIGPDDVEKLGKGKGPKVRTWLFENGEERLSRMAVSGDDCVVKPLDDRFATSLHFLNAMSKVRKDIQEWKPSTGWYDWQQVPFCSNHFTELIMKDGRTLVVPCRGQDELIGRARISPGAGWNVRDTACLAKSYAQMWLLLYFHRRDLRLMANAICSAVPANWVPTGRTTWSIHAKGEWMTTEDMLAVWNRVWIEENEWMEDKTPVERWSDVPYSGKREDIWCGSLIGTRTRATWAENIHVAINQVRSVIGEEKYVDYMSSLRRYEDTIVVEDTVL
Sequence Length
3430
Species
West Nile virus (WNV)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
380,110 Da
NCBI Official Full Name
flavivirus polyprotein
NCBI Official Symbol
flavivirus polyprotein gene
NCBI Protein Information
flavivirus polyprotein; truncated flavivirus polyprotein NS1 prime; capsid protein C; anchored capsid protein C; membrane glycoprotein precursor M; membrane glycoprotein M; envelope protein E; nonstructural protein NS1; nonstructural protein NS2A; nonstructural protein NS2B; nonstructural protein NS3; nonstructural protein NS4A; protein 2K; nonstructural protein NS4B; RNA-dependent RNA polymerase NS5; nonstructural protein NS1 prime
UniProt Protein Name
Genome polyprotein
Protein Family
UniProt Gene Name
NS4A
UniProt Synonym Gene Names
NS4B
Uniprot Description
Capsid protein C: Plays a role in virus budding by binding to the cell membrane and gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle (). During virus entry, may induce genome penetration into the host cytoplasm after hemifusion induced by the surface proteins (). Can migrate to the cell nucleus where it modulates host functions (). Overcomes the anti-viral effects of host EXOC1 by sequestering and degrading the latter through the proteasome degradation pathway (PubMed:23522008).
Research Articles on flavivirus polyprotein gene
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Product Notes
The flavivirus polyprotein gene ns4a (Catalog #AAA1015578) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2526-3430. The amino acid sequence is listed below: GGAKGRTLGE VWKERLNHMT KEEFTRYRKE AITEVDRSAA KHARREGNIT GGHPVSRGTA KLRWLVERRF LEPVGKVVDL GCGRGGWCYY MATQKRVQEV KGYTKGGPGH EEPQLVQSYG WNIVTMKSGV DVFYRPSEAS DTLLCDIGES SSSAEVEEHR TVRVLEMVED WLHRGPKEFC IKVLCPYMPK VIEKMETLQR RYGGGLIRNP LSRNSTHEMY WVSHASGNIV HSVNMTSQVL LGRMEKKTWK GPQFEEDVNL GSGTRAVGKP LLNSDTSKIK NRIERLKKEY SSTWHQDANH PYRTWNYHGS YEVKPTGSAS SLVNGVVRLL SKPWDTITNV TTMAMTDTTP FGQQRVFKEK VDTKAPEPPE GVKYVLNETT NWLWAFLARD KKPRMCSREE FIGKVNSNAA LGAMFEEQNQ WKNAREAVED PKFWEMVDEE REAHLRGECN TCIYNMMGKR EKKPGEFGKA KGSRAIWFMW LGARFLEFEA LGFLNEDHWL GRKNSGGGVE GLGLQKLGYI LKEVGTKPGG KVYADDTAGW DTRITKADLE NEAKVLELLD GEHRRLARSI IELTYRHKVV KVMRPAADGK TVMDVISRED QRGSGQVVTY ALNTFTNLAV QLVRMMEGEG VIGPDDVEKL GKGKGPKVRT WLFENGEERL SRMAVSGDDC VVKPLDDRFA TSLHFLNAMS KVRKDIQEWK PSTGWYDWQQ VPFCSNHFTE LIMKDGRTLV VPCRGQDELI GRARISPGAG WNVRDTACLA KSYAQMWLLL YFHRRDLRLM ANAICSAVPA NWVPTGRTTW SIHAKGEWMT TEDMLAVWNR VWIEENEWME DKTPVERWSD VPYSGKREDI WCGSLIGTRT RATWAENIHV AINQVRSVIG EEKYVDYMSS LRRYEDTIVV EDTVL. It is sometimes possible for the material contained within the vial of "Genome polyprotein, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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