Rat nuclear receptor subfamily 1, group H, member 2 ELISA Kit | NR1H2 elisa kit
Rat Liver X Receptor beta, LXRbeta ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
nuclear orphan receptor; may be involved in modulating 9-cis-retinoic acid signaling by interacting with retinoic acid receptor (RXR) [RGD, Feb 2006]
Uniprot Description
LXR-beta: Orphan receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. Forms a heterodimer with RXR. Ubiquitous. Belongs to the nuclear hormone receptor family. NR1 subfamily.
Protein type: Nuclear receptor
Cellular Component: cytoplasm; nucleus
Molecular Function: retinoid X receptor binding; protein binding; ligand-dependent nuclear receptor activity; DNA binding; zinc ion binding; sequence-specific DNA binding; steroid hormone receptor activity; transcription factor activity; apolipoprotein A-I receptor binding; ATPase binding
Biological Process: negative regulation of proteolysis; transcription from RNA polymerase II promoter; retinoic acid receptor signaling pathway; negative regulation of lipid transport; positive regulation of fatty acid biosynthetic process; intracellular receptor-mediated signaling pathway; transcription, DNA-dependent; positive regulation of cellular protein metabolic process; lipid homeostasis; cellular lipid metabolic process; negative regulation of transcription from RNA polymerase II promoter; negative regulation of pinocytosis; positive regulation of cholesterol transport; regulation of transcription from RNA polymerase II promoter; cholesterol homeostasis; regulation of transcription, DNA-dependent; positive regulation of lipoprotein lipase activity; positive regulation of transcription from RNA polymerase II promoter; steroid hormone mediated signaling; negative regulation of transcription, DNA-dependent
Research Articles on NR1H2
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Product Notes
The Rat NR1H2 nr1h2 (Catalog #AAA9310107) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9310107 ELISA Kit recognizes Rat NR1H2. It is sometimes possible for the material contained within the vial of "nuclear receptor subfamily 1, group H, member 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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