FMRFamide-related peptides (NPVF) Recombinant Protein | NPVF recombinant protein
Recombinant Sheep FMRFamide-related peptides (NPVF)
NCBI and Uniprot Product Information
Uniprot Description
Function: Neuropeptide RFRP-1 acts as a potent negative regulator of gonadotropin synthesis and secretion. Neuropeptides NPSF and NPVF efficiently inhibit forskolin-induced production of cAMP, but RFRP-2 shows no inhibitory activity. Neuropeptide NPVF blocks morphine-induced analgesia
By similarity. May act in concert with kisspeptin, through opposing affects, to regulate the activity of gonadotropin-releasing hormone (GnRH) neurons across the seasons, leading to an annual change in fertility and the cyclical seasonal transition from non-breeding to breeding season. Ref.2 Ref.4 Ref.5 UniProtKB Q9ESQ9 UniProtKB Q9HCQ7
Subcellular location: Secreted.
Tissue specificity: Expressed in hypothalamus, where it is localized to the dorsomedial hypothalamic nucleus (DMH), paraventricular nucleus (PVN), and to neuronal projections from the PVN to the neurosecretory zone of the median eminence. Ref.1 Ref.2 Ref.4
Induction: Expression moderately increased by a longer photoperiod. Ref.1
Sequence similarities: Belongs to the FARP (FMRFamide related peptide) family.
Research Articles on NPVF
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Product Notes
The NPVF npvf (Catalog #AAA1025335) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 58-92aa; Cytoplasmic domain. The amino acid sequence is listed below: SLTFEEVKDW GPK IKMNTPAVNK MPPSAANLPL RF. It is sometimes possible for the material contained within the vial of "FMRFamide-related peptides (NPVF), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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