Mouse natriuretic peptide precursor B ELISA Kit | NPPB elisa kit

Mouse brain natriuretic peptide, BNP ELISA Kit

Cat. Num. AAA704926

• Gene Names: Nppb; BNF; BNP; AA408272
• Reactivity: Mouse
• Synonyms: natriuretic peptide precursor B; Mouse brain natriuretic peptide; BNP ELISA Kit; BNP; brain type natriuretic peptide; natriuretic protein; NPPB elisa kit

• Reactivity: Mouse
• Specificity: This assay has high sensitivity and excellent specificity for detection of Mouse NPPB. No significant cross-reactivity or interference between Mouse NPPB and analogues was observed.
• Sequence Length: 120

• Samples: Serum, plasma, tissue homogenates, cell culture supernates
• Detection Range: 6.25 pg/ml-400 pg/ml
• Sensitivity: 1.56 pg/ml
• Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%; Three samples of known concentration were tested twenty times on one plate to assess.; Inter-assay Precision (Precision between assays): CV% is less than 10%; Three samples of known concentration were tested in twenty assays to assess.
• Detection Wavelength: 450 nm
• Sample Volume: 50-100ul
• Preparation and Storage: Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 565671787
• NCBI GeneID: 18158
• NCBI Accession #: NP_001274277.1
• NCBI GenBank Nucleotide #: NM_001287348.1
• UniProt Accession #: P40753
• Molecular Weight: 13,756 Da
• NCBI Official Full Name: natriuretic peptides B isoform 2
• NCBI Official Synonym Full Names: natriuretic peptide type B
• NCBI Official Symbol: Nppb
• NCBI Official Synonym Symbols: BNF; BNP; AA408272
• NCBI Protein Information: natriuretic peptides B; brain natriuretic peptide; type-B natriuretic factor; gamma-brain natriuretic peptide; natriuretic peptide precursor type B
• UniProt Protein Name: Natriuretic peptides B
• Protein Family: Natriuretic peptides
• UniProt Gene Name: Nppb
• UniProt Synonym Gene Names: BNP
• UniProt Entry Name: ANFB_MOUSE

NCBI Description

This gene encodes a secreted protein that belongs to the family of natriuretic peptides. Its precursor protein is processed to generate the active mature peptide. The mature peptide is a cardiac hormone that plays a role in ventricular remodeling as well as blood pressure regulation. Mice lacking this gene exhibit cardiac fibrosis. In humans this gene is associated with congestive heart failure, low bone-mineral density and postmenopausal osteoporosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]

Uniprot Description

Function: Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.