Natriuretic peptides A (NPPA) Recombinant Protein | NPPA recombinant protein
Recombinant Guinea pig Natriuretic peptides A (NPPA)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Natriuretic peptides A (NPPA); Recombinant Guinea pig Natriuretic peptides A (NPPA); Recombinant Natriuretic peptides A (NPPA); Natriuretic peptides A; Prepronatriodilatin Cleaved into the following 2 chains: 1. Cardiodilatin-related peptide; 2. CDP 3. Atrial natriuretic factor; 4. ANF; Atrial natriuretic peptide; ANP; NPPA recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-30aa; Cytoplasmic domain
Sequence
NPMYNVVSNA DLVDFKNLLD HLEEKMPLED
Species
Cavia porcellus (Guinea pig)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Related Product Information for NPPA recombinant protein
This protein belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6.
NCBI and Uniprot Product Information
Uniprot Description
Function: Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3
By similarity.
Subcellular location: Secreted.
Developmental stage: Adult.
Post-translational modification: Cleaved by CORIN upon secretion to produce the functional hormone
By similarity.
Sequence similarities: Belongs to the natriuretic peptide family.
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Product Notes
The Natriuretic peptides A (NPPA) nppa (Catalog #AAA955408) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-30aa; Cytoplasmic domain. The amino acid sequence is listed below: NPMYNVVSNA DLVDFKNLLD HLEEKMPLED. It is sometimes possible for the material contained within the vial of "Natriuretic peptides A (NPPA), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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