RNA-binding protein Nova-1 (Nova1) Recombinant Protein | Nova1 recombinant protein
Recombinant Rat RNA-binding protein Nova-1 (Nova1)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
RNA-binding protein Nova-1 (Nova1); Recombinant Rat RNA-binding protein Nova-1 (Nova1); Nova1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-474, full length protein
Sequence
MAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTIEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAIMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGFPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGVR
Sequence Length
474
Species
Rat
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Nova1 recombinant protein
This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.
NCBI and Uniprot Product Information
NCBI GI #
UniProt Accession #
Molecular Weight
48,444 Da
NCBI Official Full Name
RNA-binding protein Nova-1
UniProt Protein Name
RNA-binding protein Nova-1
Protein Family
UniProt Gene Name
Nova1
Uniprot Description
Functions to regulate alternative splicing in neurons by binding pre-mRNA in a sequence-specific manner to activate exon inclusion. It binds specifically to the sequence UCAUY (). Acts to regulate a novel glycine receptor alpha-2 chain splice variant (alpha-2N) in developing spinal cord.
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Product Notes
The Nova1 nova1 (Catalog #AAA1447342) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-474, full length protein. The amino acid sequence is listed below: MAAAPIQQNG THTGVPIDLD PPDSRKRPLE APPEAGSTKR TNTGEDGQYF LKVLIPSYAA GSIIGKGGQT IVQLQKETGA TIKLSKSKDF YPGTTERVCL IQGTIEALNA VHGFIAEKIR EMPQNVAKTE PVSILQPQTT VNPDRIKQVK IIVPNSTAGL IIGKGGATVK AIMEQSGAWV QLSQKPDGIN LQERVVTVSG EPEQNRKAVE LIIQKIQEDP QSGSCLNISY ANVTGPVANS NPTGFPYANT AEVLPTAAAA AGLLGHANLA GVAAFPAVLS GFTGNDLVAI TSALNTLASY GYNLNTLGLG LSQAAATGAL AAAAASANPA AAAANLLATY ASEASASGST AGGTAGTFAL GSLAAATAAT NGYFGAASPL AASAILGTEK STDGSKDVVE IAVPENLVGA ILGKGGKTLV EYQELTGARI QISKKGEFVP GTRNRKVTIT GTPAATQAAQ YLITQRITYE QGVR. It is sometimes possible for the material contained within the vial of "RNA-binding protein Nova-1 (Nova1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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