Mouse nicotinamide nucleotide adenylyltransferase 3 ELISA Kit | NMNAT3 elisa kit

Mouse Nicotinamide mononucleotide adenylyltransferase 3, NMNAT3 ELISA Kit

Cat. Num. AAA9316441

• Gene Names: Nmnat3; PNAT3; 4933408N02Rik
• Reactivity: Mouse
• Synonyms: nicotinamide nucleotide adenylyltransferase 3; Mouse Nicotinamide mononucleotide adenylyltransferase 3; NMNAT3 ELISA Kit; Mouse Nicotinamide mononucleotide adenylyltransferase 3 (NMNAT3) ELISA kit; PNAT3; NMN adenylyltransferase 3; NaMN adenylyltransferase 3; nicotinamide mononucleotide adenylyltransferase 3; pyridine nucleotide adenylyltransferase 3; NMNAT3 elisa kit

• Reactivity: Mouse
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
• Assay Type: Sandwich
• Detection Range: 0.625 ng/ml - 20 ng/ml.
• Sensitivity: 0.1 ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for NMNAT3 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of NMNAT3 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 21362329
• NCBI GeneID: 74080
• NCBI Accession #: NP_653116.1
• NCBI GenBank Nucleotide #: NM_144533.2
• UniProt Accession #: Q99JR6; Q58E37
• Molecular Weight: 27,703 Da
• NCBI Official Full Name: nicotinamide mononucleotide adenylyltransferase 3
• NCBI Official Synonym Full Names: nicotinamide nucleotide adenylyltransferase 3
• NCBI Official Symbol: Nmnat3
• NCBI Official Synonym Symbols: PNAT3; 4933408N02Rik
• NCBI Protein Information: nicotinamide mononucleotide adenylyltransferase 3; NMN adenylyltransferase 3; naMN adenylyltransferase 1; nicotinate-nucleotide adenylyltransferase 1
• UniProt Protein Name: Nicotinamide mononucleotide adenylyltransferase 3
• Protein Family: Nicotinamide/nicotinic acid mononucleotide adenylyltransferase
• UniProt Gene Name: Nmnat3
• UniProt Synonym Gene Names: NMN adenylyltransferase 3; NaMN adenylyltransferase 1
• UniProt Entry Name: NMNA3_MOUSE

Uniprot Description

NMNAT3: Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, can use NAD (+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+). Protects against axonal degeneration following injury. Belongs to the eukaryotic NMN adenylyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transferase; EC 2.7.7.1; Mitochondrial; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; EC 2.7.7.18; Apoptosis

Cellular Component: mitochondrion

Molecular Function: transferase activity; nucleotide binding; nicotinamide-nucleotide adenylyltransferase activity; nicotinate-nucleotide adenylyltransferase activity; catalytic activity; ATP binding; nucleotidyltransferase activity

Biological Process: NAD biosynthetic process; pyridine nucleotide biosynthetic process; response to wounding; biosynthetic process