Rat NLR family, pyrin domain containing 6 ELISA Kit | NLRP6 elisa kit
Rat NACHT, LRR and PYD domains-containing protein 6, NLRP6 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. [provided by RefSeq, Feb 2013]
Uniprot Description
NLRP6: May contribute to arginine-vasopressin (AVP)-mediated regulation of renal salt-water balance, glucose and lipid metabolism, apoptosis, and/or cell cycle. Binds arginine- vasopressin but not angiotensin II and acts as an arginine- vasopressin V2 receptor. Plays a role in modulating inflammatory responses in the colon to allow recovery from intestinal epithelial damage and limit tumorigenic potential. Protects against the development of colitis by controlling the composition of the gut microbiota by preventing colonization of the colon by harmful, inflammation-inducing bacteria such as Prevotella species. May mediate activation of CASP1 via ASC, promote activation of NF-kappa-B and stimulate cAMP accumulation. Belongs to the NLRP family.
Protein type: Receptor, misc.
Cellular Component: nuclear membrane; cytoplasm; plasma membrane
Molecular Function: peptide binding; ATP binding; vasopressin receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; response to bacterium; wound healing; negative regulation of MAPKKK cascade; regulation of inflammatory response; negative regulation of immune response; negative regulation of toll-like receptor signaling pathway; regulation of autophagy; negative regulation of I-kappaB kinase/NF-kappaB cascade
Research Articles on NLRP6
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Product Notes
The Rat NLRP6 nlrp6 (Catalog #AAA9323154) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9323154 ELISA Kit recognizes Rat NLRP6. It is sometimes possible for the material contained within the vial of "NLR family, pyrin domain containing 6, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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