Mouse Neuroligin-3 ELISA Kit | Nlgn3 elisa kit

Mouse Neuroligin-3 ELISA Kit

Cat. Num. AAA2883141

• Gene Names: Nlgn3; NL3; HNL3; A230085M13Rik
• Reactivity: Mouse
• Synonyms: Neuroligin-3; Mouse Neuroligin-3 ELISA Kit; Gliotactin homolog; Nlgn3; Nlgn3 elisa kit

• Reactivity: Mouse
• Sequence Length: 825

• Assay Type: Sandwich
• Detection Range: 0.156-10 ng/mL
• Sensitivity: 0.085 ng/mL
• Intra-Assay CV: <=6.5%
• Inter-Assay CV: <=7.8%
• Recovery: 94%
• Preparation and Storage: For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 262118191
• NCBI GeneID: 245537
• NCBI Accession #: NP_766520.2
• NCBI GenBank Nucleotide #: NM_172932.4
• UniProt Accession #: Q8BYM5; Q8BXR4; A2AGI1
• Molecular Weight: 91,162 Da
• NCBI Official Full Name: neuroligin-3
• NCBI Official Synonym Full Names: neuroligin 3
• NCBI Official Symbol: Nlgn3
• NCBI Official Synonym Symbols: NL3; HNL3; A230085M13Rik
• NCBI Protein Information: neuroligin-3
• UniProt Protein Name: Neuroligin-3
• Protein Family: Neuroligin
• UniProt Gene Name: Nlgn3
• UniProt Entry Name: NLGN3_MOUSE

Uniprot Description

NLGN3: Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system. Defects in NLGN3 may be the cause of susceptibility to autism X-linked type 1 (AUTSX1). AUTSX1 is a pervasive developmental disorder (PDD), prototypically characterized by impairments in reciprocal social interaction and communication, restricted and stereotyped patterns of interests and activities, and the presence of developmental abnormalities by 3 years of age. Defects in NLGN3 may be the cause of susceptibility to X- linked Asperger syndrome 1 (ASPGX1). ASPGX1 is considered to be a form of childhood autism. Belongs to the type-B carboxylesterase/lipase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Cell adhesion

Cellular Component: cell junction; cell soma; cell surface; dendrite; endocytic vesicle; excitatory synapse; integral to membrane; integral to plasma membrane; membrane; plasma membrane; synapse

Molecular Function: cell adhesion molecule binding; neurexin binding; receptor activity

Biological Process: adult behavior; axon extension; cell adhesion; learning; neurological control of breathing; neuron adhesion; oligodendrocyte differentiation; positive regulation of synaptic transmission, glutamatergic; positive regulation of synaptogenesis; receptor-mediated endocytosis; regulation of excitatory postsynaptic membrane potential; regulation of inhibitory postsynaptic membrane potential; regulation of synaptic transmission; regulation of synaptic transmission, glutamatergic; rhythmic synaptic transmission; social behavior; synapse organization and biogenesis; synaptic vesicle endocytosis; synaptogenesis; visual learning