NHP2 Non-Histone Chromosome Protein 2-Like Recombinant Protein | NHP2L1 recombinant protein
Recombinant Human NHP2 Non-Histone Chromosome Protein 2-Like
Gene Names
NHP2L1; FA1; FA-1; NHPX; 15.5K; OTK27; SNU13; SSFA1; SPAG12; SNRNP15-5
Purity
Greater than 95% as determined by SDS-PAGE.
Synonyms
NHP2 Non-Histone Chromosome Protein 2-Like; Recombinant Human NHP2 Non-Histone Chromosome Protein 2-Like; NHP2L1 Human; NHP2 non-histone chromosome protein 2-like Human Recombinant; FA-1; SPAG12; SNRNP15-5; SNU13; 15.5K; U4/U6.U5 tri-snRNP 15.5 kDa protein; NHP2 Non-Histone Chromosome protein 2-like 1 (S. cerevisiae); Sperm Specific Antigen 1; SSFA1; NHPX; FA1; OTK27; High Mobility Group-like Nuclear Protein 2 homolog 1; NHP2L1 recombinant protein
Host
E Coli
Purity/Purification
Greater than 95% as determined by SDS-PAGE.
Form/Format
The NHP2L1 protein solution (0.25mg/1ml) is formulated in In 20 mM Tris-HCl Buffer (pH 7.5), 100 mM NaCl, and 10% Glycerol.
Sterile Filtered clear solution.
Sterile Filtered clear solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMTEADV NPKAYPLADA HLTKKLLDLV QQSCNYKQLR KGANEATKTL NRGISEFIVM AADAEPLEII LHLPLLCEDK NVPYVFVRSK QALGRACGVS RPVIACSVTI KEGSQLKQQI QSIQQSIERL LV
Sequence Length
128
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.Please avoid freeze thaw cycles.
Related Product Information for NHP2L1 recombinant protein
Description: NHP2L1 produced in E Coli is a single, non-glycosylated polypeptide chain containing 152 amino acids (1-128a.a.) and having a molecular mass of 16.7kDa.NHP2L1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: NHP2L1 is a member of the ribosomal protein L7Ae family. NHP2L1 protein limited to the nucleus, primarily focused in the dense fibrillar component of the nucleolus. NHP2L1 directly binds to the 5' stem-loop of U4 snRNA and has a vital part in the late stage of spliceosome assembly, prior to step I of splicing catalysis.
Introduction: NHP2L1 is a member of the ribosomal protein L7Ae family. NHP2L1 protein limited to the nucleus, primarily focused in the dense fibrillar component of the nucleolus. NHP2L1 directly binds to the 5' stem-loop of U4 snRNA and has a vital part in the late stage of spliceosome assembly, prior to step I of splicing catalysis.
Product Categories/Family for NHP2L1 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
14,174 Da
NCBI Official Full Name
NHP2-like protein 1
NCBI Official Synonym Full Names
NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
NCBI Official Symbol
NHP2L1
NCBI Official Synonym Symbols
FA1; FA-1; NHPX; 15.5K; OTK27; SNU13; SSFA1; SPAG12; SNRNP15-5
NCBI Protein Information
NHP2-like protein 1; U4/U6.U5 tri-snRNP 15.5 kDa protein; [U4/U6.U5] tri-snRNP 15.5 kD RNA binding protein; high mobility group-like nuclear protein 2 homolog 1; non-histone chromosome protein 2-like 1; small nuclear ribonucleoprotein 15.5kDa (U4/U6.U5); sperm specific antigen 1
UniProt Protein Name
NHP2-like protein 1
UniProt Gene Name
NHP2L1
UniProt Synonym Gene Names
hSNU13
UniProt Entry Name
NH2L1_HUMAN
NCBI Description
Originally named because of its sequence similarity to the Saccharomyces cerevisiae NHP2 (non-histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri-snRNP. It binds to the 5' stem-loop of U4 snRNA. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
NHP2L1: Binds to the 5'-stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly. The protein undergoes a conformational change upon RNA-binding. Belongs to the ribosomal protein L7Ae family.
Protein type: RNA splicing; Nucleolus; Spliceosome; RNA-binding
Chromosomal Location of Human Ortholog: 22q13
Cellular Component: nucleoplasm; spliceosome; protein complex; nucleolus; nucleus
Molecular Function: snoRNA binding; protein binding; RNA binding
Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing; ribosome biogenesis and assembly; gene expression
Research Articles on NHP2L1
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Product Notes
The NHP2L1 nhp2l1 (Catalog #AAA144312) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MGSHMTEADV NPKAYPLADA HLTKKLLDLV QQSCNYKQLR KGANEATKTL NRGISEFIVM AADAEPLEII LHLPLLCEDK NVPYVFVRSK QALGRACGVS RPVIACSVTI KEGSQLKQQI QSIQQSIERL LV. It is sometimes possible for the material contained within the vial of "NHP2 Non-Histone Chromosome Protein 2-Like, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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