Ephexin-1 (Ngef) Recombinant Protein | Ngef recombinant protein
Recombinant Rat Ephexin-1 (Ngef)
Gene Names
Ngef; Besh3
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Ephexin-1 (Ngef); Recombinant Rat Ephexin-1 (Ngef); Ngef recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-701, full length protein
Sequence
METKNSEDQGKPQRKSVSSLWKSKHGPAEMRPELPPETAKETQNEEPRCLIPIQRNSLFNRAMRHKHKARSMSERRANDQAGDLPETRKSVNEPLAFNLPQGRLPPWRTPAQRGPGAQEASESSSTPGNGTTPEECPALTDSPTTLTEALQMIHPIPADSWRNLIEQIGLLYQEYRDKSTLQEIETRRQQDAEIQGNSDGSQAGEDNAEEEEEEEEEPASPPERRALPQICLLSNPHSRFNLWQDLPEIQSSGVLDILQPEETKLQEAMFELVTSEASYYKSLNLLVSHFMENERLKKILHPSEAHILFSNVLDVMAVSERFLLELEHRMEENIVISDVCDIVYRYAADHFSVYITYVSNQTYQERTYKQLLQEKTAFRELIAQLELDPKCKGLPLSSFLILPFQRITRLKLLVQNILKRVEEGSEREGTALDAHKELEMVVKACNEGVRKMSRTEQMISIQKKMEFKIKSVPIISHSRWLLKQGELQQMSGPKTSRTLRTKKLFREIYLFLFNDLLVICRQIPGDKYQVFDSAPRGLLRVEELEDQGQTLANVFILRLLENADDREATYMLKASSQSEMKRWMTSLAPNRRTKFVSFTSRLLDCPQVQCVHPYVAQQPDELTLELADILNILEKTEDGWIFGERLHDQERGWFPSSMTEEILNPKIRSQNLKECFRVHKMEDPQRSQNKDRRKLGSRNRQ
Sequence Length
701
Species
Rat
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
81,008 Da
NCBI Official Full Name
Ephexin-1
NCBI Official Synonym Full Names
neuronal guanine nucleotide exchange factor
NCBI Official Symbol
Ngef
NCBI Official Synonym Symbols
Besh3
NCBI Protein Information
ephexin-1
UniProt Protein Name
Ephexin-1
Protein Family
UniProt Gene Name
Ngef
Uniprot Description
Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension.
Research Articles on Ngef
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Product Notes
The Ngef ngef (Catalog #AAA1365668) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-701, full length protein. The amino acid sequence is listed below: METKNSEDQG KPQRKSVSSL WKSKHGPAEM RPELPPETAK ETQNEEPRCL IPIQRNSLFN RAMRHKHKAR SMSERRANDQ AGDLPETRKS VNEPLAFNLP QGRLPPWRTP AQRGPGAQEA SESSSTPGNG TTPEECPALT DSPTTLTEAL QMIHPIPADS WRNLIEQIGL LYQEYRDKST LQEIETRRQQ DAEIQGNSDG SQAGEDNAEE EEEEEEEPAS PPERRALPQI CLLSNPHSRF NLWQDLPEIQ SSGVLDILQP EETKLQEAMF ELVTSEASYY KSLNLLVSHF MENERLKKIL HPSEAHILFS NVLDVMAVSE RFLLELEHRM EENIVISDVC DIVYRYAADH FSVYITYVSN QTYQERTYKQ LLQEKTAFRE LIAQLELDPK CKGLPLSSFL ILPFQRITRL KLLVQNILKR VEEGSEREGT ALDAHKELEM VVKACNEGVR KMSRTEQMIS IQKKMEFKIK SVPIISHSRW LLKQGELQQM SGPKTSRTLR TKKLFREIYL FLFNDLLVIC RQIPGDKYQV FDSAPRGLLR VEELEDQGQT LANVFILRLL ENADDREATY MLKASSQSEM KRWMTSLAPN RRTKFVSFTS RLLDCPQVQC VHPYVAQQPD ELTLELADIL NILEKTEDGW IFGERLHDQE RGWFPSSMTE EILNPKIRSQ NLKECFRVHK MEDPQRSQNK DRRKLGSRNR Q. It is sometimes possible for the material contained within the vial of "Ephexin-1 (Ngef), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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