Human nuclear factor (erythroid-derived 2) -like 3 ELISA Kit | NFE2L3 elisa kit

Human Nuclear factor erythroid 2-related factor 3, NFE2L3 ELISA Kit

Cat. Num. AAA9339773

• Gene Names: NFE2L3; NRF3
• Reactivity: Human
• Synonyms: nuclear factor (erythroid-derived 2) -like 3; Human Nuclear factor erythroid 2-related factor 3; NFE2L3 ELISA Kit; Human Nuclear factor erythroid 2-related factor 3 (NFE2L3) ELISA kit; NRF3; nuclear factor erythroid 2-like 3; nuclear factor-erythroid 2 p45-related factor 3; nuclear factor-erythroid 2-related factor 3; NFE2L3 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: undiluted original Human body fluids, tissue homogenates, secretions or feces samples
• Assay Type: Quantitative Sandwich
• Detection Range: 62.5 pg/ml - 2000 pg/mL
• Sensitivity: 10 pg/mL
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for NFE2L3 elisa kit

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of NRF3 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 225735557
• NCBI GeneID: 9603
• NCBI Accession #: NP_004280.5
• NCBI GenBank Nucleotide #: NM_004289.6
• UniProt Accession #: Q9Y4A8; Q6NUS0; Q7Z498; Q86UJ4; Q86VR5; Q9UQA4
• Molecular Weight: 76,154 Da
• NCBI Official Full Name: nuclear factor erythroid 2-related factor 3
• NCBI Official Synonym Full Names: nuclear factor, erythroid 2-like 3
• NCBI Official Symbol: NFE2L3
• NCBI Official Synonym Symbols: NRF3
• NCBI Protein Information: nuclear factor erythroid 2-related factor 3; NFE2-related factor 3; NF-E2-related factor 3; nuclear factor (erythroid-derived 2)-like 3; nuclear factor, erythroid derived 2, like 3; nuclear factor-erythroid 2-related factor 3; nuclear factor-erythroid 2 p45-related factor 3
• UniProt Protein Name: Nuclear factor erythroid 2-related factor 3
• Protein Family: Nuclear factor erythroid 2-related factor
• UniProt Gene Name: NFE2L3
• UniProt Synonym Gene Names: NRF3; NF-E2-related factor 3; NFE2-related factor 3
• UniProt Entry Name: NF2L3_HUMAN

NCBI Description

This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18. [provided by RefSeq, Mar 2009]

Uniprot Description

NFE2L3: Activates erythroid-specific, globin gene expression. Belongs to the bZIP family. CNC subfamily.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 7p15.2

Cellular Component: nucleus

Molecular Function: transcription coactivator activity; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter