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SDS-Page

NEuROG3 recombinant protein

NEuROG3, 1-214aa, Human, His tag, E Coli (Denatured)

Gene Names
NEUROG3; ngn3; Atoh5; NGN-3; Math4B; bHLHa7
Applications
SDS-Page
Purity
> 85% by SDS-PAGE
Synonyms
NEuROG3; 1-214aa; Human; His tag; E Coli (Denatured); Neurogenin 3; Atoh5; bHLHa7; Math4B; ngn3; NEuROG3 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
> 85% by SDS-PAGE
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol, 0.4M urea
Concentration
0.25 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MGSSHHHHHH SSGLVPRGSH MTPQPSGAPT VQVTRETERS FPRASEDEVT CPTSAPPSPT RTRGNCAEAE EGGCRGAPRK LRARRGGRSR PKSELALSKQ RRSRRKKAND RERNRMHNLN SALDALRGVL PTFPDDAKLT KIETLRFAHN YIWALTQTLR IADHSLYALE PPAPHCGELG SPGGSPGDWG SLYSPVSQAG SLSPAASLEE RPGLLGATSS ACLSPGSLAF SDFL
Sequence Length
214
Applicable Applications for NEuROG3 recombinant protein
SDS-PAGE
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

SDS-Page

SDS-Page
Related Product Information for NEuROG3 recombinant protein
NEuROG3 is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4). Recombinant human NeuroG3 protein, fused to His-tag at N-terminus, was expressed in E Coli
Product Categories/Family for NEuROG3 recombinant protein
References
Wang J., Cortina G. et al. (2006) N. Engl. J. Med. 355:270-280

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
25.1 kDa (234aa)
NCBI Official Full Name
Neurogenin 3
NCBI Official Synonym Full Names
neurogenin 3
NCBI Official Symbol
NEUROG3
NCBI Official Synonym Symbols
ngn3; Atoh5; NGN-3; Math4B; bHLHa7
NCBI Protein Information
neurogenin-3
UniProt Protein Name
Neurogenin-3
Protein Family
UniProt Gene Name
NEUROG3
UniProt Synonym Gene Names
ATOH5; BHLHA7; NGN3; NGN-3; bHLHa7

NCBI Description

The protein encoded by this gene is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4).[provided by RefSeq, May 2010]

Uniprot Description

Acts as a transcriptional regulator. Together with NKX2-2, initiates transcriptional activation of NEUROD1. Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types ().

Research Articles on NEuROG3

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Product Notes

The NEuROG3 neurog3 (Catalog #AAA205727) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's NEuROG3 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the NEuROG3 neurog3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MTPQPSGAPT VQVTRETERS FPRASEDEVT CPTSAPPSPT RTRGNCAEAE EGGCRGAPRK LRARRGGRSR PKSELALSKQ RRSRRKKAND RERNRMHNLN SALDALRGVL PTFPDDAKLT KIETLRFAHN YIWALTQTLR IADHSLYALE PPAPHCGELG SPGGSPGDWG SLYSPVSQAG SLSPAASLEE RPGLLGATSS ACLSPGSLAF SDFL. It is sometimes possible for the material contained within the vial of "NEuROG3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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