Mouse NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) ELISA Kit | NDUFS8 elisa kit
Mouse NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial, NDUFS8 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
TYKY: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May donate electrons to ubiquinone. Defects in NDUFS8 are a cause of Leigh syndrome (LS). LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions. Belongs to the complex I 23 kDa subunit family.
Protein type: EC 1.6.99.3; EC 1.6.5.3; Energy Metabolism - oxidative phosphorylation; Mitochondrial; Oxidoreductase
Cellular Component: membrane; mitochondrion; mitochondrial respiratory chain complex I
Molecular Function: oxidoreductase activity, acting on NADH or NADPH; NADH dehydrogenase (ubiquinone) activity; metal ion binding; 4 iron, 4 sulfur cluster binding; iron-sulfur cluster binding; oxidoreductase activity; NADH dehydrogenase activity
Biological Process: mitochondrial respiratory chain complex I assembly; transport; response to oxidative stress
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Product Notes
The Mouse NDUFS8 ndufs8 (Catalog #AAA9340420) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9340420 ELISA Kit recognizes Mouse NDUFS8. It is sometimes possible for the material contained within the vial of "NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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