Mouse NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 ELISA Kit | NDUFA12 elisa kit
Mouse NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12, NDUFA12 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
NDUFA12: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Defects in NDUFA12 are the cause of Leigh syndrome (LS). An early-onset progressive neurodegenerative disorder characterized by the presence of focal, bilateral lesions in one or more areas of the central nervous system including the brainstem, thalamus, basal ganglia, cerebellum and spinal cord. Clinical features depend on which areas of the central nervous system are involved and include subacute onset of psychomotor retardation, hypotonia, ataxia, weakness, vision loss, eye movement abnormalities, seizures, and dysphagia. Belongs to the complex I NDUFA12 subunit family.
Protein type: Mitochondrial; Oxidoreductase; EC 1.6.5.3; EC 1.6.99.3
Cellular Component: mitochondrion; membrane; mitochondrial inner membrane; cytoplasm; mitochondrial respiratory chain complex I
Molecular Function: electron carrier activity; NADH dehydrogenase (ubiquinone) activity
Biological Process: transport; response to oxidative stress
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Product Notes
The Mouse NDUFA12 ndufa12 (Catalog #AAA9323218) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9323218 ELISA Kit recognizes Mouse NDUFA12. It is sometimes possible for the material contained within the vial of "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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