SHBG native protein
SHBG protein
Applications
User optimized
Purity
> 90% pure
Synonyms
SHBG; SHBG protein; Sex Hormone Binding Globulin protein; SHBG native protein
Purity/Purification
> 90% pure
Form/Format
Supplied lyophilized from 20mM NH4HCO3. May contain traces of buffer salts. Reconstitute with Phosphate buffer, with 150mM Sodium Chloride, pH >7.0.
Concentration
1.0mg per vial; lyophilized (varies by lot)
Sequence Length
402
Applicable Applications for SHBG native protein
User optimized
Source
Normal Serum/Human plasma
Species
Human
Grade
Highly Pure
Protein Type
Native
Biological Significance
SHBG transports the sex steroids testosterone, DHT and estradiol in the blood. Serum levels are increased during pregnancy, in women taking estrogens, and in men over the age of 50. Levels are reduced after menopause and in response to treatment with androgens or corticosteroids. Uses include polycystic ovary disease and tests for liver and thyroid function.
Contaminants
SDS-PAGE shows a major band corresponding to a molecular weight of approximately 45 kD.
Biohazard
Raw material tested at the donor level anf found negative for HIV I& II antibodies, HCV antibodies and HBsAg by FDA approved methods.
Preparation and Storage
Ships at 4 degree C, upon receipt store at -70 degree C long term. Avoid repeated freeze/thaw cycles
Related Product Information for SHBG native protein
Purified native Human SHBG protein
Product Categories/Family for SHBG native protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
sex hormone-binding globulin
UniProt Protein Name
Sex hormone-binding globulin
Protein Family
UniProt Gene Name
SHBG
UniProt Synonym Gene Names
SHBG; SBP; ABP; TeBG
UniProt Entry Name
SHBG_HUMAN
Uniprot Description
SHBG: Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 17p13.1
Cellular Component: extracellular region
Molecular Function: androgen binding
Biological Process: primary spermatocyte growth
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Product Notes
The SHBG shbg (Catalog #AAA537806) is a Native Protein and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's SHBG can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the SHBG shbg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SHBG, Native Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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