Human nuclear autoantigenic sperm protein (histone-binding) ELISA Kit | NASP elisa kit
Human Nuclear autoantigenic sperm protein, NASP ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryonic tissues, tumor cells, and the testis. In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa. [provided by RefSeq, Jul 2008]
Uniprot Description
NASP: Required for DNA replication, normal cell cycle progression and cell proliferation. Forms a cytoplasmic complex with HSP90 and H1 linker histones and stimulates HSP90 ATPase activity. NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA. Belongs to the NASP family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 1p34.1
Cellular Component: nucleoplasm; protein complex; nuclear chromatin; cytoplasm; nucleus
Molecular Function: histone binding; Hsp90 protein binding
Biological Process: cell proliferation; protein transport; blastocyst development; DNA replication-independent nucleosome assembly; histone exchange; cell cycle; DNA replication; DNA replication-dependent nucleosome assembly
Research Articles on NASP
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Product Notes
The Human NASP nasp (Catalog #AAA9336178) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9336178 ELISA Kit recognizes Human NASP. It is sometimes possible for the material contained within the vial of "nuclear autoantigenic sperm protein (histone-binding), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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