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Alpha-Soluble NSF Attachment Protein/SNAP-alpha/NAPA Recombinant Protein | SNAP-alpha/NAPA recombinant protein

Recombinant Human Alpha-Soluble NSF Attachment Protein/SNAP-alpha/NAPA Protein (N-6His)

Gene Names
NAPA; SNAPA
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
Alpha-Soluble NSF Attachment Protein/SNAP-alpha/NAPA; Recombinant Human Alpha-Soluble NSF Attachment Protein/SNAP-alpha/NAPA Protein (N-6His); Alpha-Soluble NSF Attachment Protein; SNAP-Alpha; N-Ethylmaleimide-Sensitive Factor Attachment Protein Alpha; NAPA; SNAPA; SNAP-alpha/NAPA recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 mum filtered solution of 20mM Tris, 150mM NaCl, pH 8.0.
Sequence Positions
Met1-Arg295
Sequence Length
295
Species
Human
Endotoxin
<1.0 EU per ug as determined by LAL test.
Fusion Tag
N-6His
Preparation and Storage
Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Related Product Information for SNAP-alpha/NAPA recombinant protein
alpha-Soluble NSF Attachment Protein (SNAP-alpha) is a member of the SNAP (Soluble NSF Attachment Protein) family. SNAP-alpha interacts with PRKCABP and disrupts the interaction between GRIA2 and PRKCABP, leading to the internalization of GRIA2. SNAP-alpha is required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. SNAP-alpha is in charge of the binding of NSF and therefore the formation of a 20S fusion particle.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Molecular Mass: 35.4 kDa
Actual Protein Molecular Mass: 35 kDa
NCBI Official Full Name
alpha-soluble NSF attachment protein
NCBI Official Synonym Full Names
NSF attachment protein alpha
NCBI Official Symbol
NAPA
NCBI Official Synonym Symbols
SNAPA
NCBI Protein Information
alpha-soluble NSF attachment protein
UniProt Protein Name
Alpha-soluble NSF attachment protein
UniProt Gene Name
NAPA
UniProt Synonym Gene Names
SNAPA; SNAP-alpha

NCBI Description

This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. The encoded protein plays a role in the completion of membrane fusion by mediating the interaction of N-ethylmaleimide-sensitive factor (NSF) with the vesicle-associated and membrane-associated SNAP receptor (SNARE) complex, and stimulating the ATPase activity of NSF. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2011]

Uniprot Description

Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (Probable). Together with GNA12 promotes CDH5 localization to plasma membrane (PubMed:15980433).

Research Articles on SNAP-alpha/NAPA

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Product Notes

The SNAP-alpha/NAPA napa (Catalog #AAA2553411) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Met1-Arg295. It is sometimes possible for the material contained within the vial of "Alpha-Soluble NSF Attachment Protein/SNAP-alpha/NAPA, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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