NAP1L4 recombinant protein

NAP1L4, 1-375aa, Human, His tag, E Coli

Cat. Num. AAA205306

• Gene Names: NAP1L4; NAP2; NAP2L; hNAP2; NAP1L4b
• Applications: SDS-Page
• Purity: > 90% by SDS-PAGE
• Synonyms: NAP1L4; 1-375aa; Human; His tag; E Coli; Nucleosome assembly protein 1-like 4; hNAP2; NAP1L4b; NAP2; NAP2L; NAP1L4 recombinant protein

• Host: E Coli
• Purity/Purification: > 90% by SDS-PAGE
• Form/Format: Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
• Concentration: 0.5 mg/ml (determined by Bradford assay) (varies by lot)
• Sequence: MGSSHHHHHH SSGLVPRGSH MGSMADHSFS DGVPSDSVEA AKNASNTEKL TDQVMQNPRV LAALQERLDN VPHTPSSYIE TLPKAVKRRI NALKQLQVRC AHIEAKFYEE VHDLERKYAA LYQPLFDKRR EFITGDVEPT DAESEWHSEN EEEEKLAGDM KSKVVVTEKA AATAEEPDPK GIPEFWFTIF RNVDMLSELV QEYDEPILKH LQDIKVKFSD PGQPMSFVLE FHFEPNDYFT NSVLTKTYKM KSEPDKADPF SFEGPEIVDC DGCTIDWKKG KNVTVKTIKK KQKHKGRGTV RTITKQVPNE SFFNFFNPLK ASGDGESLDE DSEFTLASDF EIGHFFRERI VPRAVLYFTG EAIEDDDNFE EGEEGEEEEL EGDEEGEDED DAEINPKV
• Sequence Length: 375

• Applicable Applications for NAP1L4 recombinant protein: SDS-PAGE
• Antigen Species: Human
• Tag Information: His-tag
• Preparation and Storage: Can be stored at 4 degree C short term (1-2 weeks).; For long term storage, aliquot and store at -20 degree C or -70 degree C.; Avoid repeated freezing and thawing cycles.

SDS-Page

Related Product Information for NAP1L4 recombinant protein

NAP1L4 is a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Recombinant human NAP1L4 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.

Product Categories/Family for NAP1L4 recombinant protein

Epigenomics

References

Olsen J.V., et al. (2006) Cell. 127:635-648; Nousiainen M., et al. (2006) Proc. Natl. Acad. Sci. u.S.A. 103:5391-5396;

NCBI and Uniprot Product Information

• NCBI GI #: 5174613
• NCBI GeneID: 4676
• NCBI Accession #: NP_005960
• NCBI GenBank Nucleotide #: NM_005969.3
• UniProt Accession #: Q99733; B2R6J4; F5HFY4
• Molecular Weight: 45.2 kDa (398aa), confirmed by MALDI-TOF
• NCBI Official Full Name: nucleosome assembly protein 1-like 4
• NCBI Official Synonym Full Names: nucleosome assembly protein 1 like 4
• NCBI Official Symbol: NAP1L4
• NCBI Official Synonym Symbols: NAP2; NAP2L; hNAP2; NAP1L4b
• NCBI Protein Information: nucleosome assembly protein 1-like 4
• UniProt Protein Name: Nucleosome assembly protein 1-like 4
• UniProt Gene Name: NAP1L4
• UniProt Synonym Gene Names: NAP-2

NCBI Description

This gene encodes a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. [provided by RefSeq, Jul 2008]

Uniprot Description

Acts as histone chaperone in nucleosome assembly.