Human nanos homolog 3 (Drosophila) ELISA Kit | NANOS3 elisa kit
Human Nanos homolog 3, NANOS3 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
NANOS3: Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax- dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis. Belongs to the nanos family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA-binding; Cell development/differentiation
Chromosomal Location of Human Ortholog: 19p13.13
Cellular Component: stress granule; perinuclear region of cytoplasm; cytoplasm; nucleus
Molecular Function: protein binding; zinc ion binding; RNA binding
Biological Process: regulation of translation; oogenesis; regulation of cell cycle; multicellular organismal development; negative regulation of translation; spermatogenesis; germ cell development
Research Articles on NANOS3
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Product Notes
The Human NANOS3 nanos3 (Catalog #AAA9327693) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9327693 ELISA Kit recognizes Human NANOS3. It is sometimes possible for the material contained within the vial of "nanos homolog 3 (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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